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Cortactin (CTTN) (pTyr466) antibody

Antigen

Cortactin (CTTN)
Synonyms Ems1, 1110020L01Rik, EMS1, FLJ34459, DmelCG3637, CG3637, Cttnb, MGC93456, CTTN1, P85.25, Cttn, ems1, MGC80961, CTTN, cttn, MGC137923, DKFZp459H142
Binding Site
Alternatives

pTyr466
Host
Alternatives

Rabbit
Reactivity
Alternatives

Human, Mouse (Murine)
Conjugate
Alternatives Un-conjugated
Application
Alternatives Immunohistochemistry (IHC)
2 references available
Catalog no. ABIN965920
Quantity 100ug  (100ug/100ul.)
Price 385.00 $   Plus shipping costs $45.00
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Additional Information
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Alternative name Cortactin
Immunogen The antiserum was produced against synthesized phosphopeptide derived from mouse Cortactin around the phosphorylation site of tyrosine 466 (P-V-YP-E-T).
Specificity Cortactin (Phospho-Tyr466) antibody detects endogenous levels of Cortactin only when phosphorylated at tyrosine 466.

Application Details
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Application Notes WB: 1:500~1:1000.
Concentration 100ug/100ul.
Buffer Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol
Preservative 0.02% Sodium Azide
Storage Store at -20°C/1 year.
Research Area Cancer, Cell Cycle, Cytoskeleton, Microfilaments
Restrictions For Research Use only

Publications
Application Details Alternatives back to top

Product Kinley, Weed, Weaver et al.: "Cortactin interacts with WIP in regulating Arp2/3 activation and membrane protrusion." in: Current biology : CB, Vol. 13, Issue 5, pp. 384-93, 2003 (PubMed).

Luo, Pan, Mines et al.: "CXCL12 induces tyrosine phosphorylation of cortactin, which plays a role in CXC chemokine receptor 4-mediated extracellular signal-regulated kinase activation and chemotaxis." in: The Journal of biological chemistry, Vol. 281, Issue 40, pp. 30081-93, 2006 (PubMed).

Alternatives
Application Details Publications back to top

Alternatives for antigen "Cortactin (CTTN)", type "Antibodies"
Hosts Rabbit (83), Goat (5), Mouse (5)
Reactivities Human (74), Mouse (Murine) (67), Rat (Rattus) (39), Chicken (21), Cow (Bovine) (21), Dog (Canine) (21), Horse (Equine) (18), Cat (Feline) (1), Fruit Fly (Drosophila melanogaster) (1), Xenopus laevis (1), Zebrafish (1)
Applications Western Blotting (WB) (63), ELISA (32), Immunohistochemistry (IHC) (26), Immunofluorescence (IF) (23), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (16), Immunoprecipitation (IP) (5), Immunocytochemistry (ICC) (4), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (3), Flow Cytometry (FACS) (2), Immunoelectron Microscopy (IEM) (1)
Conjugates Alexa Fluor 350 (2), Alexa Fluor 488 (2), Alexa Fluor 555 (2), Alexa Fluor 647 (2), PE,Cy5.5 (2), Biotin (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy7 (1)
Epitopes pTyr466 (12), C-Term (5), pTyr421 (3), pTyr446,Internal Region (3), N-Term (2), Tyr466 (2), Center (1), Internal Region (1), pSer3 (1), pTyr486 (1)