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CREB1 antibody (CAMP Responsive Element Binding Protein 1) (pSer129)

Details for Product anti-CREB1 Antibody No. ABIN965924, Supplier: Log in to see
Antigen
  • creb
  • CREB1
  • Creb1
  • CREB
  • 2310001E10Rik
  • 3526402H21Rik
  • AV083133
  • Creb
  • Creb-1
  • creb1
  • zgc:55598
Alternatives
anti-Human CREB1 antibody for Western Blotting
Epitope
pSer129
110
34
33
28
23
21
17
16
16
13
10
7
7
5
4
4
3
3
3
3
3
3
3
3
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
470
231
225
26
24
18
17
14
14
9
9
9
2
2
1
1
Host
Rabbit
405
71
10
1
Conjugate
This CREB1 antibody is un-conjugated
14
13
12
7
6
6
6
5
4
3
3
3
3
3
3
Application
Immunohistochemistry (IHC)
371
214
184
66
58
39
35
28
26
11
8
3
3
2
2
1
1
1
Supplier
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Immunogen The antiserum was produced against synthesized phosphopeptide derived from human CREB around the phosphorylation site of serine 129 (I-L-SP-R-R).
Specificity CREB (phospho-Ser129) antibody detects endogenous levels of CREB only when phosphorylated at serine 129.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using nonphosphopeptide corresponding to the phosphorylation site.
Alternative Name CREB (CREB1 Antibody Abstract)
Research Area Immunology, Innate Immunity, Transcription Factors
Pathways TCR Signaling, TLR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
Application Notes IHC: 1:50-1:100.
Restrictions For Research Use only
Format Liquid
Concentration 100ug/100ul.
Buffer Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Product cited in: Garat, Fankell, Erickson et al.: "Platelet-derived growth factor BB induces nuclear export and proteasomal degradation of CREB via phosphatidylinositol 3-kinase/Akt signaling in pulmonary artery smooth muscle cells." in: Molecular and cellular biology, Vol. 26, Issue 13, pp. 4934-48, 2006 (PubMed).

Rothem, Stark, Assaraf: "Impaired CREB-1 phosphorylation in antifolate-resistant cell lines with down-regulation of the reduced folate carrier gene." in: Molecular pharmacology, Vol. 66, Issue 6, pp. 1536-43, 2004 (PubMed).

Tyson, Swarthout, Jefcoat et al.: "PTH induction of transcriptional activity of the cAMP response element-binding protein requires the serine 129 site and glycogen synthase kinase-3 activity, but not casein kinase II sites." in: Endocrinology, Vol. 143, Issue 2, pp. 674-82, 2002 (PubMed).