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CREB1 antibody (CAMP Responsive Element Binding Protein 1) (pSer129)

Details for Product anti-CREB1 Antibody No. ABIN965924, Supplier: Log in to see
Antigen
  • creb
  • CREB1
  • Creb1
  • CREB
  • 2310001E10Rik
  • 3526402H21Rik
  • AV083133
  • Creb
  • Creb-1
  • creb1
  • zgc:55598
  • cAMP responsive element binding protein 1
  • cAMP responsive element binding protein 1a
  • cyclic AMP response element binding protein
  • CREB1
  • creb1
  • Creb1
  • LOC100351999
  • creb1a
  • CREB
Alternatives
anti-Human CREB1 antibody for Western Blotting
Epitope
pSer129
116
38
35
35
21
20
18
16
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15
10
7
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6
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5
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3
3
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3
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2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
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1
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1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
525
342
309
42
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36
30
27
26
24
22
15
13
10
7
7
3
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1
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1
Host
Rabbit
443
83
11
1
Conjugate
This CREB1 antibody is un-conjugated
18
15
15
7
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6
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3
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3
1
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Application
Immunohistochemistry (IHC)
426
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81
45
42
30
29
11
10
9
4
3
3
2
1
1
1
1
Options
Supplier
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Immunogen The antiserum was produced against synthesized phosphopeptide derived from human CREB around the phosphorylation site of serine 129 (I-L-SP-R-R).
Specificity CREB (phospho-Ser129) antibody detects endogenous levels of CREB only when phosphorylated at serine 129.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using nonphosphopeptide corresponding to the phosphorylation site.
Alternative Name CREB (CREB1 Antibody Abstract)
Research Area Immunology, Innate Immunity, Transcription Factors
Pathways TCR Signaling, TLR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Thyroid Hormone Synthesis, Activation of Innate immune Response, Myometrial Relaxation and Contraction
Application Notes IHC: 1:50-1:100.
Restrictions For Research Use only
Format Liquid
Concentration 100ug/100ul.
Buffer Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Product cited in: Garat, Fankell, Erickson, Reusch, Bauer, McMurtry, Klemm: "Platelet-derived growth factor BB induces nuclear export and proteasomal degradation of CREB via phosphatidylinositol 3-kinase/Akt signaling in pulmonary artery smooth muscle cells." in: Molecular and cellular biology, Vol. 26, Issue 13, pp. 4934-48, 2006 (PubMed).

Rothem, Stark, Assaraf: "Impaired CREB-1 phosphorylation in antifolate-resistant cell lines with down-regulation of the reduced folate carrier gene." in: Molecular pharmacology, Vol. 66, Issue 6, pp. 1536-43, 2004 (PubMed).

Tyson, Swarthout, Jefcoat, Partridge: "PTH induction of transcriptional activity of the cAMP response element-binding protein requires the serine 129 site and glycogen synthase kinase-3 activity, but not casein kinase II sites." in: Endocrinology, Vol. 143, Issue 2, pp. 674-82, 2002 (PubMed).