CREB1 antibody (CAMP Responsive Element Binding Protein 1) (pSer133)

Details for Product anti-CREB1 Antibody No. ABIN965925, Supplier: Log in to see
Antigen
  • creb
  • CREB1
  • Creb1
  • CREB
  • 2310001E10Rik
  • 3526402H21Rik
  • AV083133
  • Creb
  • Creb-1
  • creb1
  • zgc:55598
  • cAMP responsive element binding protein 1
  • cAMP responsive element binding protein 1a
  • cyclic AMP response element binding protein
  • CREB1
  • creb1
  • Creb1
  • LOC100351999
  • creb1a
  • CREB
Alternatives
anti-Human CREB1 antibody for Immunofluorescence (fixed cells)
Epitope
pSer133
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15
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Reactivity
Human, Mouse (Murine), Rat (Rattus)
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Host
Rabbit
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Conjugate
This CREB1 antibody is un-conjugated
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Application
Immunohistochemistry (IHC)
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11
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Options
Supplier
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Immunogen The antiserum was produced against synthesized phosphopeptide derived from human CREB around the phosphorylation site of serine 133 (R-P-SP-Y-R).
Specificity CREB (phospho-Ser133) antibody detects endogenous levels of CREB only when phosphorylated at serine 133.
Alternative Name CREB (CREB1 Antibody Abstract)
Research Area Immunology, Innate Immunity, Transcription Factors
Pathways TCR Signaling, TLR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Thyroid Hormone Synthesis, Activation of Innate immune Response, Myometrial Relaxation and Contraction, Regulation of Cell Size, Toll-Like Receptors Cascades, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma, Positive Regulation of fat Cell Differentiation
Application Notes WB: 1:500~1:1000
IHC: 1:50~1:100.
Restrictions For Research Use only
Format Liquid
Concentration 100ug/100ul.
Buffer Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Product cited in: Xing, Kornhauser, Xia, Thiele, Greenberg: "Nerve growth factor activates extracellular signal-regulated kinase and p38 mitogen-activated protein kinase pathways to stimulate CREB serine 133 phosphorylation." in: Molecular and cellular biology, Vol. 18, Issue 4, pp. 1946-55, 1998 (PubMed).

Rosenfeld, Correia, Xing, Rener, Cheung: "Structural studies of kinesin-nucleotide intermediates." in: The Journal of biological chemistry, Vol. 271, Issue 47, pp. 30212-21, 1997 (PubMed).

Background publications Tan, Rouse, Zhang, Cariati, Cohen, Comb: "FGF and stress regulate CREB and ATF-1 via a pathway involving p38 MAP kinase and MAPKAP kinase-2." in: The EMBO journal, Vol. 15, Issue 17, pp. 4629-42, 1997 (PubMed).

Hao, Lowy, Kapoor, Deffie, Liu, Lozano: "Mutation of phosphoserine 389 affects p53 function in vivo." in: The Journal of biological chemistry, Vol. 271, Issue 46, pp. 29380-5, 1997 (PubMed).