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SLC6A3 antibody (Solute Carrier Family 6 (Neurotransmitter Transporter, Dopamine), Member 3) (N-Term)

Details for Product anti-SLC6A3 Antibody No. ABIN965973, Supplier: Log in to see
Antigen
  • DAT
  • DAT1
  • Dat1
  • PKDYS
  • SLC6A3
Epitope
N-Term
36
15
14
7
5
2
2
2
1
1
1
1
1
1
1
1
1
1
Reactivity
Human
90
36
33
7
4
1
Host
Rabbit
83
13
9
2
Clonality
Polyclonal
Conjugate
This SLC6A3 antibody is un-conjugated
3
2
2
2
1
1
1
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (IHC)
87
43
27
19
12
11
4
3
3
3
1
1
1
Supplier
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Immunogen Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to N-terminal residues of human DAT(Sodium-dependent dopamine transporter)
Purification Purified by antigen-specific affinity chromatography.
Alternative Name DAT (SLC6A3 Antibody Abstract)
Background DAT(Sodium-dependent dopamine transporter)is an amine transporter. DAT terminates the action of dopamine by its high affinity sodium-dependent reuptake into presynaptic terminals. This protein is the target of psychomotor stimulants such as amphetamines or cocaine. It belongs to the sodium: neurotransmitter symporter (SNF) family.
Application Notes ELISA, Western blotting: 1µg/ml for 2hrs.
Restrictions For Research Use only
Format Liquid
Buffer This antibody is stored in PBS, 50% glycerol
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Background publications Greenwood, Alexander, Keck, McElroy, Sadovnick, Remick, Kelsoe: "Evidence for linkage disequilibrium between the dopamine transporter and bipolar disorder." in: American journal of medical genetics, Vol. 105, Issue 2, pp. 145-51, 2001

Torres, Yao, Mohn, Quan, Kim, Levey, Staudinger, Caron: "Functional interaction between monoamine plasma membrane transporters and the synaptic PDZ domain-containing protein PICK1." in: Neuron, Vol. 30, Issue 1, pp. 121-34, 2001

Vandenbergh, Thompson, Cook, Bendahhou, Nguyen, Krasowski, Zarrabian, Comings, Sellers, Tyndale, George, ODowd, Uhl: "Human dopamine transporter gene: coding region conservation among normal, Tourette's disorder, alcohol dependence and attention-deficit hyperactivity disorder populations." in: Molecular psychiatry, Vol. 5, Issue 3, pp. 283-92, 2000

Donovan, Vandenbergh, Perry, Bird, Ingersoll, Nanthakumar, Uhl: "Human and mouse dopamine transporter genes: conservation of 5'-flanking sequence elements and gene structures." in: Brain research. Molecular brain research, Vol. 30, Issue 2, pp. 327-35, 1995

Product cited in: Pristupa, Wilson, Hoffman, Kish, Niznik: "Pharmacological heterogeneity of the cloned and native human dopamine transporter: disassociation of [3H]WIN 35,428 and [3H]GBR 12,935 binding." in: Molecular pharmacology, Vol. 45, Issue 1, pp. 125-35, 1994

Vandenbergh, Persico, Uhl: "A human dopamine transporter cDNA predicts reduced glycosylation, displays a novel repetitive element and provides racially-dimorphic TaqI RFLPs." in: Brain research. Molecular brain research, Vol. 15, Issue 1-2, pp. 161-6, 1992

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