Der1-Like Domain Family, Member 2 (DERL2) (N-Term) antibody

Catalog No. ABIN965991

Product Details

Target: Der1-Like Domain Family, Member 2 (DERL2)

Binding Specificity: N-Term

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: Un-conjugated

Application: Immunohistochemistry (IHC)

Purification: Purified by antigen-specific affinity chromatography.

Immunogen: Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to N-terminal residues of human DERL2 (Derlin-2)

Application Details

Application Notes: ELISA, Western blotting: 1µg/ml for 2hrs.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: This antibody is stored in PBS, 50% glycerol

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

References

Ying, Yu, Xu: "Cloning and characterization of F-LANa, upregulated in human liver cancer." in: Biochemical and biophysical research communications, Vol. 286, Issue 2, pp. 394-400, (2001) (PubMed).

Target Details

Target: Der1-Like Domain Family, Member 2 (DERL2)

Alternative Name: DERL2 (DERL2 Products)

Synonyms: F-LAN-1 antibody, F-LANa antibody, FLANa antibody, BC005682 antibody, CGI-101 antibody, Derlin-2 antibody, F-lana antibody, Flana antibody, RP23-83I13.8 antibody, derl2 antibody, zgc:110436 antibody, CG14899 antibody, Cg14899 antibody, DER1 antibody, Dmel\\CG14899 antibody, derlin 2 antibody, Der1-like domain family, member 2 antibody, derlin-2 antibody, derlin-2.1 antibody, derlin 2 S homeolog antibody, Derlin-2 antibody, DERL2 antibody, Derl2 antibody, derl2 antibody, PVX_117040 antibody, CpipJ_CPIJ012528 antibody, MCYG_03163 antibody, VDBG_06959 antibody, LOAG_05811 antibody, MGYG_00329 antibody, derl2.S antibody, Der-2 antibody

Background: DERL2 (Derlin-2) may be involved in the degradation process of specific misfolded endoplasmic reticulum (ER) luminal proteins. Its precise role is however unclear. In contrast to DER1, it is not involved in the degradation of MHC class I heavy chains in cas of infection by the cytomegalovirus. DERL2 may play a role in cell proliferation.

Pathways: ER-Nucleus Signaling, Feeding Behaviour