Epidermal Growth Factor Receptor (EGFR) (pSer1070) antibody

Details for Product No. ABIN966032
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Antigen
Synonyms
C-erb, CG10079, D-EGFR, D-Egf, DEGFR, DER, DER flb, DER/EGFR, DER/faint little ball, DER/top, DER/torpedo, DER1, DEgfr, Degfr, Der, DmHD-33, Dmel\\CG10079, EFG-R, EGF-R, EGFR, EGFr, EGfr, EK2-6, Egf,  ... show more
C-erb, CG10079, D-EGFR, D-Egf, DEGFR, DER, DER flb, DER/EGFR, DER/faint little ball, DER/top, DER/torpedo, DER1, DEgfr, Degfr, Der, DmHD-33, Dmel\\CG10079, EFG-R, EGF-R, EGFR, EGFr, EGfr, EK2-6, Egf, Egf-r, EgfR, El, Elp, Elp-1, Elp-B1, Elp-B1RB1, HD-33, TOP, Torpedo/DER, Torpedo/Egfr, c-erbB, d-egf-r, dEGFR, dEGFR1, dEgfr, der, egfr, flb, l(2)05351, l(2)09261, l(2)57DEFa, l(2)57EFa, l(2)57Ea, mor1, top, top/DER, top/flb, torpedo/Egfr, torpedo/egfr, EGFR12, EGFR15, egfr1, Erbb2, ERBB, ERBB1, HER1, PIG61, mENA, ErbB-1, Errp, 9030024J15Rik, AI552599, Erbb, Errb1, Wa5, wa-2, wa2 show less
Epitope
pSer1070
(91), (58), (52), (48), (47), (43), (43), (41), (41), (39), (38), (28), (25), (23), (20), (20), (18), (17), (17), (17), (17), (15), (15), (13), (13), (13), (13), (13), (12), (12), (10), (9), (9), (8), (8), (8), (8), (8), (7), (7), (7), (6), (6), (6), (5), (5), (5), (5), (4), (4), (4), (4), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Human, Mouse (Murine), Rat (Rattus)
(1435), (672), (620), (160), (145), (124), (77), (7), (6), (3), (2), (1)
Host
Rabbit
(1129), (281), (22), (14), (8), (1), (1)
Conjugate
Un-conjugated
(72), (47), (36), (26), (25), (25), (25), (25), (25), (25), (25), (19), (10), (10), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Immunohistochemistry (IHC)
(967), (431), (309), (249), (243), (173), (146), (141), (95), (70), (53), (19), (4), (4), (3), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Pubmed 4 references available
Quantity 100 μg
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Catalog No. ABIN966032
398.75 $
Plus shipping costs $45.00

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  • +1 404 474 4654
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Immunogen The antiserum was produced against synthesized phosphopeptide derived from human EGFR around the phosphorylation site of serine 1070 (R-Y-SP-S-D).
Specificity EGFR (phospho-Ser1070) antibody detects endogenous levels of EGFR only when phosphorylated at serine1070.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Alternative Name EGFR
Research Area Cancer, Tyrosine Kinases, Growth Factors, Hormones, Receptors
Application Notes WB: 1:500~1:1000
IHC: 1:50~1:100.
Restrictions For Research Use only
Format Liquid
Concentration 100ug/100ul.
Buffer Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Product cited in: Heisermann, Gill: "Epidermal growth factor receptor threonine and serine residues phosphorylated in vivo." in: The Journal of biological chemistry, Vol. 263, Issue 26, pp. 13152-8, 1988 (PubMed).

Gamou, Shimizu: "Calphostin-C stimulates epidermal growth factor receptor phosphorylation and internalization via light-dependent mechanism." in: Journal of cellular physiology, Vol. 158, Issue 1, pp. 151-9, 1994 (PubMed).

Gamou, Shimizu: "Hydrogen peroxide preferentially enhances the tyrosine phosphorylation of epidermal growth factor receptor." in: FEBS letters, Vol. 357, Issue 2, pp. 161-4, 1995 (PubMed).

Feinmesser, Wicks, Taverner et al.: "Ca2+/calmodulin-dependent kinase II phosphorylates the epidermal growth factor receptor on multiple sites in the cytoplasmic tail and serine 744 within the kinase domain to regulate signal generation." in: The Journal of biological chemistry, Vol. 274, Issue 23, pp. 16168-73, 1999 (PubMed).

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