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EGFR antibody (Epidermal Growth Factor Receptor) (pTyr1092)

Details for Product anti-EGFR Antibody No. ABIN966035, Supplier: Log in to see
Antigen
  • 9030024J15Rik
  • AI552599
  • C-erb
  • c-erbB
  • CG10079
  • D-Egf
  • d-egf-r
  • D-EGFR
  • Degfr
  • dEgfr
  • DEgfr
  • DEGFR
  • dEGFR
  • dEGFR1
  • der
  • DER
  • Der
  • DER/EGFR
  • DER/faint little ball
  • DER/top
  • DER/torpedo
  • DER1
  • DER flb
  • Dmel\\CG10079
  • DmHD-33
  • EFG-R
  • Egf
  • EGF-R
  • Egf-r
  • EgfR
  • EGfr
  • EGFr
  • EGFR
  • egfr
  • egfr1
  • EGFR12
  • EGFR15
  • EK2-6
  • El
  • Elp
  • Elp-1
  • Elp-B1
  • Elp-B1RB1
  • ERBB
  • Erbb
  • ErbB-1
  • ERBB1
  • Erbb2
  • Errb1
  • Errp
  • flb
  • HD-33
  • HER1
  • l(2)05351
  • l(2)09261
  • l(2)57DEFa
  • l(2)57Ea
  • l(2)57EFa
  • mENA
  • mor1
  • PIG61
  • TOP
  • top
  • top/DER
  • top/flb
  • Torpedo/DER
  • Torpedo/Egfr
  • torpedo/Egfr
  • torpedo/egfr
  • wa-2
  • wa2
  • Wa5
Alternatives
anti-Human EGFR antibody for Western Blotting
Epitope
pTyr1092
146
140
58
57
52
51
50
48
46
45
44
44
35
33
32
30
30
25
24
23
23
23
23
22
22
19
18
17
16
14
14
13
13
13
13
13
13
13
13
11
10
10
10
9
9
9
8
8
8
8
8
8
7
7
6
6
5
5
4
4
4
4
4
4
4
3
3
3
3
3
3
3
3
3
3
3
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
2159
748
610
23
14
14
13
10
8
7
4
2
1
1
1
1
1
Host
Rabbit
1377
692
63
45
4
2
Conjugate
This EGFR antibody is un-conjugated
93
74
64
55
45
43
25
24
23
21
21
21
21
21
21
21
20
19
19
19
19
19
19
19
19
19
19
2
2
2
1
Application
Immunohistochemistry (IHC)
1321
568
511
449
420
250
232
184
86
76
71
55
25
11
11
9
8
5
4
3
3
3
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
Supplier
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Immunogen The antiserum was produced against synthesized phosphopeptide derived from human EGFR around the phosphorylation site of tyrosine1092 (P-E-YP-I-N).
Specificity The antiserum was produced against synthesized phosphopeptide derived from human EGFR around the phosphorylation site of tyrosine1092 (P-E-YP-I-N).
Alternative Name EGFR (EGFR Antibody Abstract)
Research Area Cancer, Tyrosine Kinases, Growth Factors, Hormones, Receptors
Pathways NF-kappaB Signaling, RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
Application Notes WB: 1:500~1:1000
IHC: 1:50~1:100.
Restrictions For Research Use only
Format Liquid
Concentration 100ug/100ul.
Buffer Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Background publications Saito, Okada, Ohshima, Yamada, Sato, Uehara, Shimizu, Pessin, Mori: "Differential activation of epidermal growth factor (EGF) receptor downstream signaling pathways by betacellulin and EGF." in: Endocrinology, Vol. 145, Issue 9, pp. 4232-43, 2004 (PubMed).

Buerger, Nagel-Wolfrum, Kunz, Wittig, Butz, Hoppe-Seyler, Groner: "Sequence-specific peptide aptamers, interacting with the intracellular domain of the epidermal growth factor receptor, interfere with Stat3 activation and inhibit the growth of tumor cells." in: The Journal of biological chemistry, Vol. 278, Issue 39, pp. 37610-21, 2003 (PubMed).

Product cited in: Pao, Miller, Zakowski, Doherty, Politi, Sarkaria, Singh, Heelan, Rusch, Fulton, Mardis, Kupfer, Wilson, Kris, Varmus: "EGF receptor gene mutations are common in lung cancers from "never smokers" and are associated with sensitivity of tumors to gefitinib and erlotinib." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 101, Issue 36, pp. 13306-11, 2004 (PubMed).

Wang, Sun, Paller: "Ganglioside GM3 blocks the activation of epidermal growth factor receptor induced by integrin at specific tyrosine sites." in: The Journal of biological chemistry, Vol. 278, Issue 49, pp. 48770-8, 2003 (PubMed).

Ranft, Hennemann, Beck: "[Significance of the tuberculin reaction from the current viewpoint]." in: Deutsche medizinische Wochenschrift (1946), Vol. 101, Issue 36, pp. 1330-2, 1976 (PubMed).