anti-ELK1 antibody (ELK1, Member of ETS Oncogene Family) (pSer383)

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Antigen
Synonyms Elk-1, BEC2, ELK1, Kv12.3
Alternatives
Epitope
pSer383
(80), (40), (35), (28), (9), (8), (8), (5), (4), (3), (3), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Human, Mouse (Murine), Rat (Rattus)
(341), (188), (176), (11), (4), (4), (2), (2), (2), (2), (1), (1)
Host
Rabbit
(306), (39)
Conjugate
This ELK1 antibody is un-conjugated
(5), (5), (5), (5), (4), (4), (3), (3), (3), (3), (3), (3), (3), (2), (2)
Application
Immunohistochemistry (IHC)
(221), (147), (102), (45), (41), (38), (36), (7), (6), (3), (2), (1), (1)
Pubmed 6 references available
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Quantity 100 μg
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Immunogen The antiserum was produced against synthesized phosphopeptide derived from human Elk-1 around the phosphorylation site of serine 383 (T-L-SP-P-I).
Specificity Elk-1 (phospho-Ser383) antibody detects endogenous levels of Elk-1 only when phosphorylated at serine 383.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Alternative Name Elk-1 (ELK1 Antibody Abstract)
Pathways MAPK Signaling, Neurotrophin Signaling Pathway
Application Notes WB: 1:500~1:1000
IHC: 1:50~1:100.
Restrictions For Research Use only
Format Liquid
Concentration 100ug/100ul
Buffer Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Product cited in: Conner: "Is there a secular answer to euthanasia, American style?" in: Angelicum, Vol. 73, pp. 381-400, 1999 (PubMed).

Cavigelli, Dolfi, Claret et al.: "Induction of c-fos expression through JNK-mediated TCF/Elk-1 phosphorylation." in: The EMBO journal, Vol. 14, Issue 23, pp. 5957-64, 1996 (PubMed).

Xing, Ginty, Greenberg: "Coupling of the RAS-MAPK pathway to gene activation by RSK2, a growth factor-regulated CREB kinase." in: Science (New York, N.Y.), Vol. 273, Issue 5277, pp. 959-63, 1996 (PubMed).

Marais, Wynne, Treisman: "The SRF accessory protein Elk-1 contains a growth factor-regulated transcriptional activation domain." in: Cell, Vol. 73, Issue 2, pp. 381-93, 1993 (PubMed).

Janknecht, Ernst, Pingoud et al.: "Activation of ternary complex factor Elk-1 by MAP kinases." in: The EMBO journal, Vol. 12, Issue 13, pp. 5097-104, 1994 (PubMed).

Kortenjann, Thomae, Shaw: "Inhibition of v-raf-dependent c-fos expression and transformation by a kinase-defective mutant of the mitogen-activated protein kinase Erk2." in: Molecular and cellular biology, Vol. 14, Issue 7, pp. 4815-24, 1994 (PubMed).

Catalog No. ABIN966058
$398.75
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