ELK1 antibody (ELK1, Member of ETS Oncogene Family) (pSer383)

Details for Product anti-ELK1 Antibody No. ABIN966058, Supplier: Log in to see
Antigen
  • Elk-1
  • BEC2
  • ELK1
  • Kv12.3
  • ETS domain-containing protein Elk-1
  • ELK1, member of ETS oncogene family
  • potassium voltage-gated channel, subfamily H (eag-related), member 4
  • Tsp_02690
  • ELK1
  • Elk1
  • elk1
  • KCNH4
Alternatives
anti-Human ELK1 antibody for Immunofluorescence (fixed cells)
Epitope
pSer383
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37
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12
8
4
4
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2
1
1
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1
1
1
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1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
364
206
194
23
18
14
13
12
7
6
3
3
3
3
2
1
1
Host
Rabbit
286
81
Conjugate
This ELK1 antibody is un-conjugated
7
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Application
Immunohistochemistry (IHC)
250
163
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56
43
40
33
7
3
3
3
2
1
1
Options
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Immunogen The antiserum was produced against synthesized phosphopeptide derived from human Elk-1 around the phosphorylation site of serine 383 (T-L-SP-P-I).
Specificity Elk-1 (phospho-Ser383) antibody detects endogenous levels of Elk-1 only when phosphorylated at serine 383.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Alternative Name Elk-1 (ELK1 Antibody Abstract)
Pathways MAPK Signaling, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades, Signaling of Hepatocyte Growth Factor Receptor
Application Notes WB: 1:500~1:1000
IHC: 1:50~1:100.
Restrictions For Research Use only
Format Liquid
Concentration 100ug/100ul
Buffer Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Product cited in: Conner: "Is there a secular answer to euthanasia, American style?" in: Angelicum, Vol. 73, pp. 381-400, 1999 (PubMed).

Cavigelli, Dolfi, Claret, Karin: "Induction of c-fos expression through JNK-mediated TCF/Elk-1 phosphorylation." in: The EMBO journal, Vol. 14, Issue 23, pp. 5957-64, 1996 (PubMed).

Xing, Ginty, Greenberg: "Coupling of the RAS-MAPK pathway to gene activation by RSK2, a growth factor-regulated CREB kinase." in: Science (New York, N.Y.), Vol. 273, Issue 5277, pp. 959-63, 1996 (PubMed).

Kortenjann, Thomae, Shaw: "Inhibition of v-raf-dependent c-fos expression and transformation by a kinase-defective mutant of the mitogen-activated protein kinase Erk2." in: Molecular and cellular biology, Vol. 14, Issue 7, pp. 4815-24, 1994 (PubMed).

Janknecht, Ernst, Pingoud, Nordheim: "Activation of ternary complex factor Elk-1 by MAP kinases." in: The EMBO journal, Vol. 12, Issue 13, pp. 5097-104, 1994 (PubMed).

Marais, Wynne, Treisman: "The SRF accessory protein Elk-1 contains a growth factor-regulated transcriptional activation domain." in: Cell, Vol. 73, Issue 2, pp. 381-93, 1993 (PubMed).