ELK1 antibody (ELK1, Member of ETS Oncogene Family) (pSer389)

Details for Product anti-ELK1 Antibody No. ABIN966059, Supplier: Log in to see
Antigen
  • Elk-1
  • BEC2
  • ELK1
  • Kv12.3
  • ETS domain-containing protein Elk-1
  • ELK1, member of ETS oncogene family
  • potassium voltage-gated channel, subfamily H (eag-related), member 4
  • Tsp_02690
  • ELK1
  • Elk1
  • elk1
  • KCNH4
Alternatives
anti-Human ELK1 antibody for Western Blotting
Epitope
pSer389
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Reactivity
Human, Mouse (Murine), Rat (Rattus)
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Host
Rabbit
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Conjugate
This ELK1 antibody is un-conjugated
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Application
Immunohistochemistry (IHC)
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Options
Supplier
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Immunogen The antiserum was produced against synthesized phosphopeptide derived from human Elk1 around the phosphorylation site of serine 389 (P-R-SP-P-A).
Specificity Elk-1 (phospho-Ser389) antibody detects endogenous levels of Elk-1 only when phosphorylated at serine 389.
Alternative Name Elk-1 (ELK1 Antibody Abstract)
Pathways MAPK Signaling, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades, Signaling of Hepatocyte Growth Factor Receptor
Application Notes IHC: 1:50-1:100.
Restrictions For Research Use only
Format Liquid
Concentration 100ug/100ul.
Buffer Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Background publications Cavigelli, Dolfi, Claret, Karin: "Induction of c-fos expression through JNK-mediated TCF/Elk-1 phosphorylation." in: The EMBO journal, Vol. 14, Issue 23, pp. 5957-64, 1996 (PubMed).

Hill, Treisman: "Transcriptional regulation by extracellular signals: mechanisms and specificity." in: Cell, Vol. 80, Issue 2, pp. 199-211, 1995 (PubMed).

Janknecht, Ernst, Pingoud, Nordheim: "Activation of ternary complex factor Elk-1 by MAP kinases." in: The EMBO journal, Vol. 12, Issue 13, pp. 5097-104, 1994 (PubMed).

Kortenjann, Thomae, Shaw: "Inhibition of v-raf-dependent c-fos expression and transformation by a kinase-defective mutant of the mitogen-activated protein kinase Erk2." in: Molecular and cellular biology, Vol. 14, Issue 7, pp. 4815-24, 1994 (PubMed).

Product cited in: Marais, Wynne, Treisman: "The SRF accessory protein Elk-1 contains a growth factor-regulated transcriptional activation domain." in: Cell, Vol. 73, Issue 2, pp. 381-93, 1993 (PubMed).

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