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EPH Receptor B6 antibody

EPHB6 Reactivity: Human WB, ELISA, IHC Host: Mouse Monoclonal 8E7H12 unconjugated
Catalog No. ABIN966077
  • Target See all EPH Receptor B6 (EPHB6) Antibodies
    EPH Receptor B6 (EPHB6)
    Reactivity
    • 79
    • 32
    • 22
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 75
    • 4
    • 1
    • 1
    Mouse
    Clonality
    • 76
    • 5
    Monoclonal
    Conjugate
    • 33
    • 9
    • 8
    • 7
    • 6
    • 6
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This EPH Receptor B6 antibody is un-conjugated
    Application
    • 60
    • 51
    • 38
    • 13
    • 7
    • 7
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    Purification
    Purified
    Immunogen
    Purified recombinant fragment of EphB6 expressed in E. Coli.
    Clone
    8E7H12
    Isotype
    IgG1
    Top Product
    Discover our top product EPHB6 Primary Antibody
  • Application Notes
    Western Bloting: 1/500 - 1/2000.
    Immunohistochemistry: 1/200 - 1/1000.
    ELISA: Propose dilution 1/10000.
    Not yet tested in other applications.
    Determining optimal working dilutions by titration test.
    Restrictions
    For Research Use only
  • Buffer
    PBS
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C
  • Ogawa, Wada, Okada, Harada, Nakajima, Pasquale, Tsuyama: "EphB2 and ephrin-B1 expressed in the adult kidney regulate the cytoarchitecture of medullary tubule cells through Rho family GTPases." in: Journal of cell science, Vol. 119, Issue Pt 3, pp. 559-70, (2006) (PubMed).

    Matsuoka, Obama, Kelly, Matsui, Nakamoto: "Biphasic functions of the kinase-defective Ephb6 receptor in cell adhesion and migration." in: The Journal of biological chemistry, Vol. 280, Issue 32, pp. 29355-63, (2005) (PubMed).

  • Target
    EPH Receptor B6 (EPHB6)
    Alternative Name
    EphB6 (EPHB6 Products)
    Synonyms
    CEK9 antibody, EPHB5 antibody, Cekl antibody, Mep antibody, HEP antibody, EPH receptor B6 antibody, Eph receptor B6 antibody, EPHB6 antibody, Ephb6 antibody
    Background
    EPH receptor B6 (EphB6), with 1006-amino acid protein(~ 110 kDa), belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. Eph receptors and ephrin ligands are membrane-bound cell-cell communication molecules with well-defined functions in development. EphB6 is expressed both in a variety of embryonic and adult tissues. EphB6 is a unique member in the Eph family of receptor tyrosine kinases in that its kinase domain contains several alterations in conserved amino acids and is catalytically inactive. EphB6 can both positively and negatively regulate cell adhesion and migration and tyrosine phosphorylation of the receptor by an Src family kinase acts as the molecular switch for the functional transition.
    Synonyms: HEP, MGC129910, MGC129911
    Gene ID
    2051
    Pathways
    RTK Signaling, Hormone Transport
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