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C14orf1 antibody (N-Term)

C14orf1 Reactivity: Human, Mouse IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN966089
  • Target See all C14orf1 products
    C14orf1 (Chromosome 14 Open Reading Frame 1 (C14orf1))
    Binding Specificity
    • 2
    • 1
    • 1
    N-Term
    Reactivity
    • 5
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human, Mouse
    Host
    • 5
    Rabbit
    Clonality
    • 5
    Polyclonal
    Conjugate
    • 5
    This C14orf1 antibody is un-conjugated
    Application
    • 4
    • 3
    • 1
    • 1
    Immunohistochemistry (IHC)
    Purification
    Purified by antigen-specific affinity chromatography.
    Immunogen
    Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to N-terminal residues of mouse ERG28(Probable ergosterol biosynthetic protein 28)
  • Application Notes
    ELISA, Western blotting: 1µg/ml for 2hrs.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    This antibody is stored in PBS, 50% glycerol
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
  • Mo, Valachovic, Bard: "The ERG28-encoded protein, Erg28p, interacts with both the sterol C-4 demethylation enzyme complex as well as the late biosynthetic protein, the C-24 sterol methyltransferase (Erg6p)." in: Biochimica et biophysica acta, Vol. 1686, Issue 1-2, pp. 30-6, (2004) (PubMed).

  • Target
    C14orf1 (Chromosome 14 Open Reading Frame 1 (C14orf1))
    Alternative Name
    ERG28 (C14orf1 Products)
    Synonyms
    ERG28 antibody, NET51 antibody, homolog of yeast ergosterol28 antibody, T27I1.5 antibody, T27I1_5 antibody, C7H14orf1 antibody, ergosterol biosynthesis 28 homolog antibody, ergosterol biosynthetic protein 28 antibody, ergosterol biosynthesis protein antibody, ERG28 antibody, LOC781060 antibody, ANI_1_490024 antibody, AOR_1_898014 antibody
    Background
    ERG28(Probable ergosterol biosynthetic protein 28) has a role as a scaffold to help anchor ERG25, ERG26 and ERG27 to the endoplasmic reticulum. ERG28 may also be responsible for facilitating their interaction. The ERG28-encoded protein, Erg28p, interacts with both the sterol C-4 demethylation enzyme complex as well as the late biosynthetic protein, the C-24 sterol methyltransferase (Erg6p). ERG28 acts as a scaffold to tether ERG27 and other 4,4-demethylation-related enzymes, forming a demethylation enzyme complex, in the endoplasmic reticulum. ERG28 interacts with ERG25, ERG26 and ERG27. It also interacts with ERG1, ERG3, ERG5, ERG6 and ERG11.
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