Estrogen Receptor 1 (ESR1) (pSer167) antibody

Details for Product No. ABIN966101
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Antigen
Synonyms
ACTGP1, ACT1GP1, HY-psi-gamma-AC6, ER[b]2, ER[b]a, zfER[b]2, zfER-beta2, XER, era, esr, esra, nr3a1, ERbeta, xesr-1, ERalpha, xlERalpha1, xlERalpha2, LOC398733, LOC398734, 2610524P08Rik, 9130407C09Rik ... show more
ACTGP1, ACT1GP1, HY-psi-gamma-AC6, ER[b]2, ER[b]a, zfER[b]2, zfER-beta2, XER, era, esr, esra, nr3a1, ERbeta, xesr-1, ERalpha, xlERalpha1, xlERalpha2, LOC398733, LOC398734, 2610524P08Rik, 9130407C09Rik, AU019798, Era, M-ERA, MERA-S, MERA-W, ERA, ERAL1A, H-ERA, HERA-A, HERA-B, er, esr1, ER, ESR, ESRA, ESTRR, NR3A1, ER-alpha, Esr, RNESTROR, ERALPHA, ER[a], eralpha, zfER[a], ESR1, AA420328, AU041214, ERa, Estr, Estra, Nr3a1 show less
Epitope
pSer167
(65), (45), (45), (44), (40), (26), (21), (16), (11), (10), (10), (9), (9), (8), (8), (8), (8), (8), (7), (7), (7), (6), (6), (5), (5), (4), (4), (4), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Human
(691), (281), (156), (54), (40), (27), (14), (12), (4), (2), (2), (1), (1), (1), (1), (1)
Host
Rabbit
(555), (169), (8), (3), (2)
Conjugate
Un-conjugated
(24), (20), (19), (10), (10), (10), (10), (10), (10), (10), (10), (7), (7), (7)
Application
Immunohistochemistry (IHC)
(539), (230), (221), (197), (116), (100), (69), (50), (34), (30), (18), (10), (9), (4), (3), (3), (2), (2), (1), (1), (1), (1), (1)
Pubmed 3 references available
Quantity 100 μg
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Catalog No. ABIN966101
398.75 $
Plus shipping costs $45.00

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Immunogen The antiserum was produced against synthesized phosphopeptide derived from human Estrogen Receptor- around the phosphorylation site of serine 167 (L-A-SP-T-N).
Specificity Estrogen Receptor- (phospho-Ser167) antibody detects endogenous levels of Estrogen Receptor- only when phosphorylated at serine167.
Alternative Name Estrogen Receptor-alpha
Application Notes WB: 1:500~1:1000
IHC: 1:50~1:100.
Restrictions For Research Use only
Format Liquid
Concentration 100ug/100ul.
Buffer Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Product cited in: Campbell, Bhat-Nakshatri, Patel et al.: "Phosphatidylinositol 3-kinase/AKT-mediated activation of estrogen receptor alpha: a new model for anti-estrogen resistance." in: The Journal of biological chemistry, Vol. 276, Issue 13, pp. 9817-24, 2001 (PubMed).

Sun, Paciga, Feldman et al.: "Phosphatidylinositol-3-OH Kinase (PI3K)/AKT2, activated in breast cancer, regulates and is induced by estrogen receptor alpha (ERalpha) via interaction between ERalpha and PI3K." in: Cancer research, Vol. 61, Issue 16, pp. 5985-91, 2001 (PubMed).

Shah, Rowan: "The Src kinase pathway promotes tamoxifen agonist action in Ishikawa endometrial cells through phosphorylation-dependent stabilization of estrogen receptor (alpha) promoter interaction and elevated steroid receptor coactivator 1 activity." in: Molecular endocrinology (Baltimore, Md.), Vol. 19, Issue 3, pp. 732-48, 2005 (PubMed).

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