Estrogen Receptor 1 (ESR1) (pSer167) antibody

Antigen: Estrogen Receptor 1 (ESR1)

Synonyms: AAC2, PNAT, ACTGP1, ACT1GP1, HY-psi-gamma-AC6, 7B4, CD144, FLJ17376, ER, ESR, Era, ESRA, NR3A1, DKFZp686N23123, ERa, Estr, ER[a], Estra, Nr3a1, ERalpha, AA420328, AU041214, ER-alpha, ER[b], Estrb, ERbeta, Esr, RNESTROR, eralpha, zfER[a], ESR2, ERB, Errra, ERRalpha, ER[b]1, zfER[b]1, MGC103724, zfER-beta1, ER[b]2, ER[b]a, zfER[b]2, zfER-beta2, erb, esrb, estrb, nr3a2, er-beta, esr-beta, XER, era, esr, esra, nr3a1, xesr-1, xlERalpha1, xlERalpha2, CERB, ER-beta, ESR1, LOC398733, LOC398734, ESRRA, ESTRRA, ERBETA, ERALPHA, err1, erra, esrral, erralpha, esrl1, nr3b1, MGC147343, er, LOC100125507

Binding Site: pSer167

Host: Rabbit

Reactivity: Human

Conjugate: Un-conjugated

Application: Immunohistochemistry (IHC)

Catalog no.: ABIN966101

Additional Information

Alternative name: Estrogen Receptor-alpha

Immunogen: The antiserum was produced against synthesized phosphopeptide derived from human Estrogen Receptor- around the phosphorylation site of serine 167 (L-A-SP-T-N).

Specificity: Estrogen Receptor- (phospho-Ser167) antibody detects endogenous levels of Estrogen Receptor- only when phosphorylated at serine167.

Synonyms: AAC2, PNAT, ACTGP1, ACT1GP1, HY-psi-gamma-AC6, 7B4, CD144, FLJ17376, ER, ESR, Era, ESRA, NR3A1, DKFZp686N23123, ERa, Estr, ER[a], Estra, Nr3a1, ERalpha, AA420328, AU041214, ER-alpha, ER[b], Estrb, ERbeta, Esr, RNESTROR, eralpha, zfER[a], ESR2, ERB, Errra, ERRalpha, ER[b]1, zfER[b]1, MGC103724, zfER-beta1, ER[b]2, ER[b]a, zfER[b]2, zfER-beta2, erb, esrb, estrb, nr3a2, er-beta, esr-beta, XER, era, esr, esra, nr3a1, xesr-1, xlERalpha1, xlERalpha2, CERB, ER-beta, ESR1, LOC398733, LOC398734, ESRRA, ESTRRA, ERBETA, ERALPHA, err1, erra, esrral, erralpha, esrl1, nr3b1, MGC147343, er, LOC100125507

Application Details

Application Notes: WB: 1:500~1:1000
IHC: 1:50~1:100.

Concentration: 100ug/100ul.

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol

Preservative: 0.02% Sodium Azide

Storage: Store at -20°C/1 year.

Restrictions: For Research Use only

Publications

Product: Campbell, Bhat-Nakshatri, Patel et al.: "Phosphatidylinositol 3-kinase/AKT-mediated activation of estrogen receptor alpha: a new model for anti-estrogen resistance." in: The Journal of biological chemistry, Vol. 276, Issue 13, pp. 9817-24, 2001 (PubMed).

Sun, Paciga, Feldman et al.: "Phosphatidylinositol-3-OH Kinase (PI3K)/AKT2, activated in breast cancer, regulates and is induced by estrogen receptor alpha (ERalpha) via interaction between ERalpha and PI3K." in: Cancer research, Vol. 61, Issue 16, pp. 5985-91, 2001 (PubMed).

Shah, Rowan: "The Src kinase pathway promotes tamoxifen agonist action in Ishikawa endometrial cells through phosphorylation-dependent stabilization of estrogen receptor (alpha) promoter interaction and elevated steroid receptor coactivator 1 activity." in: Molecular endocrinology (Baltimore, Md.), Vol. 19, Issue 3, pp. 732-48, 2005 (PubMed).