Ezrin (EZR) (pTyr353) antibody

Details for Product No. ABIN966110
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Antigen
Synonyms ezr, vil2, wu:fc05c03, wu:fj31d06, cvil, cvl, CVIL, CVL, VIL2, AW146364, R75297, Vil2, p81, ATVLN2, T11A7.16, T11A7_16, villin 2
Epitope
pTyr353
(31), (26), (23), (21), (17), (15), (12), (6), (5), (3), (3), (3), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Human, Mouse (Murine)
(261), (181), (158), (52), (38), (36), (36), (12), (2), (2), (1)
Host
Rabbit
(229), (22), (10), (2)
Conjugate
Un-conjugated
(9), (6), (6), (5), (5), (5), (5), (5), (5), (5), (5)
Application
Immunohistochemistry (IHC)
(213), (95), (50), (47), (32), (16), (6), (4), (4), (3), (1), (1)
Pubmed 3 references available
Quantity 100 μg
Options
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Catalog No. ABIN966110
385.00 $
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Immunogen The antiserum was produced against synthesized phosphopeptide derived from human Ezrin around the phosphorylation site of tyrosine 353 (Q-D-YP-E-E).
Specificity Ezrin (phospho-Tyr353) antibody detects endogenous levels of Ezrin only when phosphorylated at tyrosine 353.
Alternative Name Ezrin
Research Area Cancer, Cytoskeleton, Microfilaments
Application Notes WB: 1:500~1:1000.
Restrictions For Research Use only
Format Liquid
Concentration 100ug/100ul.
Buffer Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Product cited in: Gautreau, Poullet, Louvard et al.: "Ezrin, a plasma membrane-microfilament linker, signals cell survival through the phosphatidylinositol 3-kinase/Akt pathway." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 96, Issue 13, pp. 7300-5, 1999 (PubMed).

Wang, Pfeiffer, Gaarde: "Activation of SRC tyrosine kinases in response to ICAM-1 ligation in pulmonary microvascular endothelial cells." in: The Journal of biological chemistry, Vol. 278, Issue 48, pp. 47731-43, 2003 (PubMed).

Zhao, Shiue, Palkon et al.: "Ezrin regulates NHE3 translocation and activation after Na+-glucose cotransport." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 101, Issue 25, pp. 9485-90, 2004 (PubMed).

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