FAF1 antibody (N-Term)

Catalog No. ABIN966117

Product Details anti-FAF1 Antibody

Target: FAF1 (Fas (TNFRSF6) Associated Factor 1 (FAF1))

Binding Specificity: N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FAF1 antibody is un-conjugated

Application: Western Blotting (WB)

Cross-Reactivity: Mouse (Murine), Rat (Rattus)

Cross-Reactivity (Details): No cross reactivity with other proteins.

Characteristics: Rabbit IgG polyclonal antibody for FAS-associated factor 1 ( FAF1) detection. Tested with WB in Human, Mouse, Rat.

Immunogen: A synthetic peptide corresponding to a sequence at the N-terminal of human FAF1, identical to the related mouse and rat sequences.< br/>Immunogen was affinity purified.

Isotype: IgG

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 µg/mL.

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Preservative: Sodium azide, Thimerosal (Merthiolate)

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: At -20 °C for one year. After reconstitution, at 4 °C for one month. It can also be aliquotted and stored frozen at -20 °C for a longer time.

References for anti-FAF1 antibody (ABIN966117)

Park, Jang, Lee, Lee, Kim: "Fas-associated factor-1 inhibits nuclear factor-kappaB (NF-kappaB) activity by interfering with nuclear translocation of the RelA (p65) subunit of NF-kappaB." in: The Journal of biological chemistry, Vol. 279, Issue 4, pp. 2544-9, (2004) (PubMed).

Ryu, Chae, Lee, Kim: "Identification and characterization of human Fas associated factor 1, hFAF1." in: Biochemical and biophysical research communications, Vol. 262, Issue 2, pp. 388-94, (1999) (PubMed).

Target Details for FAF1

Target: FAF1 (Fas (TNFRSF6) Associated Factor 1 (FAF1))

Alternative Name: FAS-associated factor 1(hFAF1) (FAF1 Products)

Synonyms: faf1 antibody, MGC53741 antibody, MGC80303 antibody, FAF1 antibody, zgc:55752 antibody, wu:fc25h12 antibody, HFAF1s antibody, UBXD12 antibody, UBXN3A antibody, hFAF1 antibody, AA408698 antibody, Dffrx antibody, Fam antibody, Fas (TNFRSF6) associated factor 1 S homeolog antibody, Fas (TNFRSF6) associated factor 1 L homeolog antibody, Fas associated factor 1 antibody, Fas (TNFRSF6) associated factor 1 antibody, Fas-associated factor 1 antibody, faf1.S antibody, faf1.L antibody, FAF1 antibody, faf1 antibody, Faf1 antibody

Background: Fas-associated factor-1 (FAF1) is a Fas-binding pro-apoptotic protein that is a component of the death-inducing signaling complex in Fas-mediated apoptosis. FAF1 is involved in negative regulation of NF-kappaB activation. In addition to the previously known function as a component of the Fas death-inducing signaling complex, i. e. NF-kappaB activity suppressor by cytoplasmic retention of NF-kappaB p65 via physical interaction. hFAF1 was expressed abundantly in testis, skeletal muscle, and heart as 2. 8 kb mRNA. Polyclonal antibody against hFAF1 detected 74 kD protein, a deduced protein size from the ORF and 40 kD protein in some cell lines.

Pathways: Maintenance of Protein Location