FAK antibody (PTK2 Protein tyrosine Kinase 2) (pTyr925)

Details for Product anti-PTK2 Antibody No. ABIN966122, Supplier: Log in to see
Antigen
  • FADK
  • FAK
  • FAK1
  • FRNK
  • PPP1R71
  • p125FAK
  • pp125FAK
  • PTK2
  • Fadk
  • mKIAA4203
  • fak
  • fak1a
  • ptk2
  • ptk2a
  • wu:fa18c04
  • zgc:66114
  • CG33007
  • CG3969
  • CG43741
  • DPR2
  • DRODPR2
  • DmHD-11
  • Dmel\\CG43741
  • Dmel_CG33007
  • Dmel_CG3969
  • HD-11
  • PR2
  • PR2/ACK
  • Rp2
  • dACK
  • CG10023
  • CT28129
  • DFAK
  • DFak
  • DFak56
  • Dfak
  • Dfak56
  • DmFAK
  • Dmel\\CG10023
  • Fak56
  • Fak56D
  • fak56
  • protein tyrosine kinase 2
  • PTK2 protein tyrosine kinase 2
  • protein tyrosine kinase 2a
  • Activated Cdc42 kinase-like
  • Focal adhesion kinase
  • PTK2
  • ptk2
  • Ptk2
  • ptk2.1
  • Ack-like
  • Fak
Alternatives
anti-Human FAK antibody for Immunofluorescence (fixed cells)
Epitope
pTyr925
79
66
62
50
47
35
27
22
21
17
17
16
15
15
14
10
9
9
8
8
7
5
5
5
4
4
4
4
4
4
3
3
3
3
3
3
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
709
473
437
51
26
24
12
11
11
10
10
8
6
6
5
4
3
3
3
3
2
1
1
Host
Rabbit
620
114
3
2
1
1
Conjugate
This FAK antibody is un-conjugated
17
17
15
12
12
11
11
11
11
11
11
11
10
10
3
2
2
2
Application
Immunohistochemistry (IHC)
508
192
158
142
133
115
64
29
18
9
9
7
6
3
2
Options
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Immunogen The antiserum was produced against synthesized phosphopeptide derived from human FAK around the phosphorylation site of tyrosine 925 (K-V-YP-E-N).
Specificity FAK (phospho-Tyr925) antibody detects endogenous levels of FAK only when phosphorylated at tyrosine 925.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Alternative Name FAK (PTK2 Antibody Abstract)
Research Area Cancer, Extracellular Matrix, Tyrosine Kinases, Angiogenesis, Kinases/Phosphatases
Pathways Response to Growth Hormone Stimulus, CXCR4-mediated Signaling Events, Smooth Muscle Cell Migration, Signaling of Hepatocyte Growth Factor Receptor
Application Notes WB: 1:500~1:1000.
Restrictions For Research Use only
Format Liquid
Concentration 100ug/100ul.
Buffer Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Background publications Sanders, Basson: "p130cas but not paxillin is essential for Caco-2 intestinal epithelial cell spreading and migration on collagen IV." in: The Journal of biological chemistry, Vol. 280, Issue 25, pp. 23516-22, 2005 (PubMed).

Cherubini, Hofmann, Pillozzi, Guasti, Crociani, Cilia, Di Stefano, Degani, Balzi, Olivotto, Wanke, Becchetti, Defilippi, Wymore, Arcangeli: "Human ether-a-go-go-related gene 1 channels are physically linked to beta1 integrins and modulate adhesion-dependent signaling." in: Molecular biology of the cell, Vol. 16, Issue 6, pp. 2972-83, 2005 (PubMed).

Product cited in: Toriumi, Hiraoka, Watanabe, Yoshida: "Pioglitazone reduces monocyte adhesion to vascular endothelium under flow by modulating RhoA GTPase and focal adhesion kinase." in: FEBS letters, Vol. 553, Issue 3, pp. 419-22, 2003 (PubMed).