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PTK2 Protein tyrosine Kinase 2 (PTK2) antibody

Details for Product No. ABIN966125
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Antigen
Synonyms FADK, FAK, FAK1, FRNK, PPP1R71, p125FAK, pp125FAK, Fadk, mKIAA4203
Reactivity
Human, Mouse (Murine), Rat (Rattus)
(555), (368), (358), (117), (109), (108), (2), (2), (2), (1), (1)
Host
Rabbit
(509), (61), (2)
Clonality
Polyclonal
Conjugate
Un-conjugated
(14), (14), (14), (13), (13), (13), (13), (13), (13), (13), (13), (1), (1), (1)
Application
Immunohistochemistry (IHC)
(392), (174), (134), (130), (91), (77), (34), (33), (9), (6), (3), (2), (1)
Pubmed 5 references available
Quantity 100 µg
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Catalog No. ABIN966125
385.00 $
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Immunogen The antiserum was produced against synthesized non-phosphopeptide derived from human FAK around the phosphorylation site of tyrosine 925.
Specificity FAK (Ab-925) antibody detects endogenous levels of total FAK protein.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Alternative Name FAK
Application Notes WB: 1:500~1:1000
IHC: 1:50~1:100.
Restrictions For Research Use only
Format Liquid
Concentration 100ug/100ul.
Buffer Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Product cited in: Schmeil: "[Special therapy]." in: Zahntechnik; Zeitschrift für Theorie und Praxis der wissenschaftlichen Zahntechnik, Vol. 14, Issue 10, pp. 430-3 contd, 1974 (PubMed).

Shi, Boettiger: "A novel mode for integrin-mediated signaling: tethering is required for phosphorylation of FAK Y397." in: Molecular biology of the cell, Vol. 14, Issue 10, pp. 4306-15, 2003 (PubMed).

Toriumi, Hiraoka, Watanabe et al.: "Pioglitazone reduces monocyte adhesion to vascular endothelium under flow by modulating RhoA GTPase and focal adhesion kinase." in: FEBS letters, Vol. 553, Issue 3, pp. 419-22, 2003 (PubMed).

Cherubini, Hofmann, Pillozzi et al.: "Human ether-a-go-go-related gene 1 channels are physically linked to beta1 integrins and modulate adhesion-dependent signaling." in: Molecular biology of the cell, Vol. 16, Issue 6, pp. 2972-83, 2005 (PubMed).

Sanders, Basson: "p130cas but not paxillin is essential for Caco-2 intestinal epithelial cell spreading and migration on collagen IV." in: The Journal of biological chemistry, Vol. 280, Issue 25, pp. 23516-22, 2005 (PubMed).

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