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FAK antibody (PTK2 Protein tyrosine Kinase 2)

Details for Product anti-PTK2 Antibody No. ABIN966125, Supplier: Log in to see
Antigen
  • FADK
  • FAK
  • FAK1
  • FRNK
  • PPP1R71
  • p125FAK
  • pp125FAK
  • Fadk
  • mKIAA4203
Reactivity
Human, Mouse (Murine), Rat (Rattus)
613
357
330
21
6
5
3
3
2
2
2
1
1
1
Host
Rabbit
555
91
2
2
1
Clonality
Polyclonal
Conjugate
This FAK antibody is un-conjugated
18
17
16
13
12
12
11
11
11
11
11
11
3
2
2
1
Application
Immunohistochemistry (IHC)
443
181
154
124
97
82
51
18
12
7
6
5
3
2
1
Supplier
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Immunogen The antiserum was produced against synthesized non-phosphopeptide derived from human FAK around the phosphorylation site of tyrosine 925.
Specificity FAK (Ab-925) antibody detects endogenous levels of total FAK protein.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Alternative Name FAK (PTK2 Antibody Abstract)
Pathways
Application Notes WB: 1:500~1:1000
IHC: 1:50~1:100.
Restrictions For Research Use only
Format Liquid
Concentration 100ug/100ul.
Buffer Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Product cited in: Sanders, Basson: "p130cas but not paxillin is essential for Caco-2 intestinal epithelial cell spreading and migration on collagen IV." in: The Journal of biological chemistry, Vol. 280, Issue 25, pp. 23516-22, 2005 (PubMed).

Toriumi, Hiraoka, Watanabe et al.: "Pioglitazone reduces monocyte adhesion to vascular endothelium under flow by modulating RhoA GTPase and focal adhesion kinase." in: FEBS letters, Vol. 553, Issue 3, pp. 419-22, 2003 (PubMed).

Shi, Boettiger: "A novel mode for integrin-mediated signaling: tethering is required for phosphorylation of FAK Y397." in: Molecular biology of the cell, Vol. 14, Issue 10, pp. 4306-15, 2003 (PubMed).

Schmeil: "[Special therapy]." in: Zahntechnik; Zeitschrift für Theorie und Praxis der wissenschaftlichen Zahntechnik, Vol. 14, Issue 10, pp. 430-3 contd, 1974 (PubMed).

Background publications Cherubini, Hofmann, Pillozzi et al.: "Human ether-a-go-go-related gene 1 channels are physically linked to beta1 integrins and modulate adhesion-dependent signaling." in: Molecular biology of the cell, Vol. 16, Issue 6, pp. 2972-83, 2005 (PubMed).