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FGF7 antibody (Fibroblast Growth Factor 7) (N-Term)

Details for Product anti-FGF7 Antibody No. ABIN966138, Supplier: Log in to see
Antigen
  • KGF
  • HBGF-7
  • kgf
  • Kgf
  • FGF-7
Alternatives
anti-Human FGF7 antibody for Enzyme Immunoassay
Epitope
N-Term, AA 51-65
13
13
12
9
6
5
4
4
4
2
Reactivity
Human
89
24
19
1
1
1
1
Host
85
9
Clonality
Polyclonal
Conjugate
This FGF7 antibody is un-conjugated
11
7
6
3
3
3
1
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
68
48
20
15
11
11
5
4
4
2
1
1
Supplier
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Immunogen A synthetic peptide corresponding to a sequence at the N-terminal of human FGF7 (51-65aa), identical to the related mouse and rat sequence.
Alternative Name FGF7 (FGF7 Antibody Abstract)
Background Keratinocyte growth factor is a protein that in humans is encoded by the FGF7 gene. The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein is a potent epithelial cell-specific growth factor, whose mitogenic activity is predominantly exhibited in keratinocytes but not in fibroblasts and endothelial cells. Studies of mouse and rat homologs of this gene implicated roles in morphogenesis of epithelium, reepithelialization of wounds, hair development and early lung organogenesis.
Pathways RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
Application Notes WB: The detection limit for FGF7 is approximately 5ng/lane under non-reducing and reducing conditions.
Restrictions For Research Use only
Reconstitution 0.2ml of distilled water will yield a concentration of 500µg/ml.
Buffer Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4
Preservative Thimerosal (Merthiolate), Sodium azide
Storage -20 °C
Product cited in: Eberlé, Dubreuil, Mattei et al.: "The human PRR2 gene, related to the human poliovirus receptor gene (PVR), is the true homolog of the murine MPH gene." in: Gene, Vol. 159, Issue 2, pp. 267-72, 1995 (PubMed).

Kelley, Pech, Seuanez et al.: "Emergence of the keratinocyte growth factor multigene family during the great ape radiation." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 89, Issue 19, pp. 9287-91, 1992 (PubMed).