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FOXO1 antibody (Forkhead Box O1) (pSer256)

Details for Product anti-FOXO1 Antibody No. ABIN966146, Supplier: Login to see New
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Antigen
Synonyms FOXO1, FOXO1A, fkh1, fkhr, foxo1a, xFoxO1, FKH1, FKHR, AI876417, Afxh, Fkhr1, Foxo1a, Fkhr, FoxO1A, FoxO1a.1, foxo1, zgc:153388
Alternatives
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Epitope
pSer256
(51), (40), (26), (24), (19), (16), (16), (15), (14), (10), (9), (8), (6), (5), (5), (5), (5), (4), (4), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Human, Mouse (Murine), Rat (Rattus)
(380), (189), (164), (17), (17), (8), (4), (3), (2), (2), (1), (1), (1), (1)
Host
Rabbit
(302), (62), (21), (2)
Conjugate
This FOXO1 antibody is un-conjugated
(7), (7), (6), (5), (4), (4), (4), (4), (4), (4), (4), (4), (1), (1), (1)
Application
Immunohistochemistry (IHC)
(298), (143), (115), (82), (67), (47), (35), (9), (7), (5), (4), (3), (3), (2), (1), (1)
Pubmed 2 references available
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Quantity 100 μg
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Immunogen The antiserum was produced against synthesized phosphopeptide derived from human FKHR around the phosphorylation site of serine 256 (A-A-SP-M-D).
Specificity FKHR (phospho-Ser256) antibody detects endogenous levels of FKHR only when phosphorylated at serine 256.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Alternative Name FKHR (FOXO1 Antibody Abstract)
Pathways PI3K-Akt Signaling, Cell Division Cycle, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
Application Notes WB: 1:500~1:1000
IHC: 1:50~1:100.
Restrictions For Research Use only
Format Liquid
Concentration 100ug/100ul.
Buffer Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Product cited in: Smith, Norton, Gorospe et al.: "Phosphorylation of p66Shc and forkhead proteins mediates Abeta toxicity." in: The Journal of cell biology, Vol. 169, Issue 2, pp. 331-9, 2005 (PubMed).

Background publications Gan, Zheng, Chabot et al.: "Nuclear/cytoplasmic shuttling of the transcription factor FoxO1 is regulated by neurotrophic factors." in: Journal of neurochemistry, Vol. 93, Issue 5, pp. 1209-19, 2005 (PubMed).

Catalog No. ABIN966146
$398.75
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