Forkhead Box O3 (FOXO3) (pSer253) antibody

Details for Product No. ABIN966150
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Antigen
Synonyms
AF6q21, FKHRL1, FKHRL1P2, FOXO2, FOXO3A, Fkhr2, C76856, Foxo3a, 1110048B16Rik, 2010203A17Rik, Fkhrl1, FoxO3A, FOXO-3, FOXO3, zgc:92176, wu:fb50g02, wu:fi33f07, foxo3, foxo3l, xFox06, foxo3a, xfoxo3, f ... show more
AF6q21, FKHRL1, FKHRL1P2, FOXO2, FOXO3A, Fkhr2, C76856, Foxo3a, 1110048B16Rik, 2010203A17Rik, Fkhrl1, FoxO3A, FOXO-3, FOXO3, zgc:92176, wu:fb50g02, wu:fi33f07, foxo3, foxo3l, xFox06, foxo3a, xfoxo3, foxO3, foxO show less
Epitope
pSer253
(37), (26), (16), (15), (12), (12), (12), (3), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Human, Mouse (Murine), Rat (Rattus)
(191), (110), (94), (57), (55), (53), (51), (4), (2), (1)
Host
Rabbit
(149), (38), (11)
Conjugate
Un-conjugated
(4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4)
Application
Immunohistochemistry (IHC)
(141), (94), (81), (46), (40), (40), (20), (5), (4), (1), (1)
Pubmed 5 references available
Catalog no. ABIN966150
Quantity 100 µg
Price
385.00 $   Plus shipping costs $45.00
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Immunogen The antiserum was produced against synthesized phosphopeptide derived from human FKHRL1 around the phosphorylation site of serine 253 (A-V-SP-M-D).
Specificity FKHRL1 (phospho-Ser253) antibody detects endogenous levels of FKHRL1 only when phosphorylated at serine 253.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Alternative Name FKHRL1
Application Notes WB: 1:500~1:1000
IHC: 1:50~1:100.
Restrictions For Research Use only
Format Liquid
Concentration 100ug/100ul.
Buffer Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol
Preservative Sodium azide
Storage -20 °C
Product cited in: Goode, Grauer, Gums: "Infectious vaginitis. Selecting therapy and preventing recurrence." in: Postgraduate medicine, Vol. 96, Issue 6, pp. 85-8, 91-8, 1994 (PubMed).

Brunet, Bonni, Zigmond et al.: "Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor." in: Cell, Vol. 96, Issue 6, pp. 857-68, 1999 (PubMed).

Brunet, Park, Tran et al.: "Protein kinase SGK mediates survival signals by phosphorylating the forkhead transcription factor FKHRL1 (FOXO3a)." in: Molecular and cellular biology, Vol. 21, Issue 3, pp. 952-65, 2001 (PubMed).

Essafi, Fernández de Mattos, Hassen et al.: "Direct transcriptional regulation of Bim by FoxO3a mediates STI571-induced apoptosis in Bcr-Abl-expressing cells." in: Oncogene, Vol. 24, Issue 14, pp. 2317-29, 2005 (PubMed).

Smith, Norton, Gorospe et al.: "Phosphorylation of p66Shc and forkhead proteins mediates Abeta toxicity." in: The Journal of cell biology, Vol. 169, Issue 2, pp. 331-9, 2005 (PubMed).

Hosts (149), (38), (11)
Reactivities (191), (110), (94), (57), (55), (53), (51), (4), (2), (1)
Applications (141), (94), (81), (46), (40), (40), (20), (5), (4), (1), (1)
Conjugates (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4)
Epitopes (37), (26), (16), (15), (12), (12), (12), (3), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
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