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FOXP3 antibody (Forkhead Box P3)

Details for Product anti-FOXP3 Antibody No. ABIN966163, Supplier: Log in to see
Antigen
  • foxp3
  • FOXP3
  • AIID
  • DIETER
  • IPEX
  • PIDX
  • XPID
  • JM2
  • scurfin
  • sf
  • RGD1562112
  • forkhead box P3
  • forkhead box P3a
  • transcription factor foxp3
  • FOXP3
  • foxp3a
  • LOC100348270
  • foxp3
  • Foxp3
Reactivity
Mouse (Murine)
418
273
44
44
12
8
8
5
4
2
2
1
1
1
Host
255
187
38
31
Clonality
Monoclonal
Conjugate
This FOXP3 antibody is un-conjugated
37
30
21
19
19
18
18
10
9
9
9
7
6
6
5
5
3
3
3
3
2
Application
Flow Cytometry (FACS), ELISA, Western Blotting (WB)
292
203
179
102
87
77
75
59
29
17
5
5
5
4
2
2
2
1
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Isotype IgG2b
Specificity Ni-NTA purified truncated recombinant Foxp3 expressed in E. Coli strain BL21 (DE3)
Purification Antibodies are purified by protein A affinity chromatography
Alternative Name Foxp3 (FOXP3 Antibody Abstract)
Background The transcription factor Foxp family included Foxp1, Foxp2, and Foxp3. The Foxp3(50KDa)played a key role in CD4(+) CD25(+) regulatory T cell function and represents a specific marker for these cells. Despite its strong association with regulatory T cell function, in humans little was known about the frequency of CD4(+)CD25(+) cells that express FOXP3 protein nor the distribution of these cells in vivo. FOXP3 may be a master regulatory gene and a more specific marker of regulatory T cells than other T cells.
Gene ID 50943
Application Notes Western Blot: 1: 200- 1: 1,000
FCM: 1: 100- 1: 500
ELISA: Propose dilution 1: 10,000.
Determining optimal working dilutions by titration test.
Restrictions For Research Use only
Format Liquid
Storage -20 °C
Background publications Roncador, Brown, Maestre, Hue, Martínez-Torrecuadrada, Ling, Pratap, Toms, Fox, Cerundolo, Powrie, Banham: "Analysis of FOXP3 protein expression in human CD4+CD25+ regulatory T cells at the single-cell level." in: European journal of immunology, Vol. 35, Issue 6, pp. 1681-91, 2005 (PubMed).