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FOXP3 antibody (Forkhead Box P3)

Details for Product anti-FOXP3 Antibody No. ABIN966163, Supplier: Log in to see
Antigen
  • foxp3
  • FOXP3
  • AIID
  • DIETER
  • IPEX
  • PIDX
  • XPID
  • JM2
  • scurfin
  • sf
  • RGD1562112
Reactivity
Mouse (Murine)
325
184
57
22
22
21
16
12
9
8
2
2
1
1
Host
205
131
66
32
Clonality
Monoclonal
Conjugate
This FOXP3 antibody is un-conjugated
36
30
22
19
15
13
11
10
6
4
3
3
3
3
3
2
2
2
2
2
2
2
2
1
1
Application
Flow Cytometry (FACS), ELISA, Western Blotting (WB)
239
166
140
86
38
31
29
29
18
17
15
6
5
4
2
2
2
1
1
Supplier
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Isotype IgG2b
Specificity Ni-NTA purified truncated recombinant Foxp3 expressed in E. Coli strain BL21 (DE3)
Purification Antibodies are purified by protein A affinity chromatography
Alternative Name Foxp3 (FOXP3 Antibody Abstract)
Background The transcription factor Foxp family included Foxp1, Foxp2, and Foxp3. The Foxp3(50KDa)played a key role in CD4(+) CD25(+) regulatory T cell function and represents a specific marker for these cells. Despite its strong association with regulatory T cell function, in humans little was known about the frequency of CD4(+)CD25(+) cells that express FOXP3 protein nor the distribution of these cells in vivo. FOXP3 may be a master regulatory gene and a more specific marker of regulatory T cells than other T cells.
Gene ID 50943
Application Notes Western Blot: 1: 200- 1: 1,000
FCM: 1: 100- 1: 500
ELISA: Propose dilution 1: 10,000.
Determining optimal working dilutions by titration test.
Restrictions For Research Use only
Format Liquid
Storage -20 °C
Background publications Roncador, Brown, Maestre et al.: "Analysis of FOXP3 protein expression in human CD4+CD25+ regulatory T cells at the single-cell level." in: European journal of immunology, Vol. 35, Issue 6, pp. 1681-91, 2005 (PubMed).