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GRB2-Associated Binding Protein 1 (GAB1) (pTyr627) antibody

Antigen

GRB2-Associated Binding Protein 1 (GAB1)
Synonyms GAB1
Binding Site
Alternatives

pTyr627
Host
Alternatives

Rabbit
Reactivity
Alternatives

Human, Mouse (Murine)
Conjugate
Alternatives Un-conjugated
Application
Alternatives Immunohistochemistry (IHC)
3 references available
Catalog no. ABIN966173
Quantity 100ug  (100ug/100ul.)  (Variants)
Price 385.00 $   Plus shipping costs $45.00
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Additional Information
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Alternative name Gab1
Immunogen The antiserum was produced against synthesized phosphopeptide derived from human Gab1 around the phosphorylation site of tyrosine 627 (V-E-YP-L-D).
Specificity Gab1 (phospho-Tyr627) antibody detects endogenous levels of Gab1 only when phosphorylated at tyrosine 627.

Application Details
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Application Notes WB: 1:500~1:1000.
Concentration 100ug/100ul.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using nonphosphopeptide corresponding to the phosphorylation site.
Buffer Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol
Preservative 0.02% Sodium Azide
Storage Store at -20°C/1 year.
Restrictions For Research Use only

Publications
Application Details Alternatives Variants back to top

Product Kameda, Risinger, Han et al.: "Identification of epidermal growth factor receptor- Grb2-associated binder-1-SHP-2 complex formation and its functional loss during neoplastic cell progression." in: Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research, Vol. 12, Issue 6, pp. 307-18, 2001 (PubMed).

Osawa, Masuda, Kusano et al.: "Evidence for a role of platelet endothelial cell adhesion molecule-1 in endothelial cell mechanosignal transduction: is it a mechanoresponsive molecule?" in: The Journal of cell biology, Vol. 158, Issue 4, pp. 773-85, 2002 (PubMed).

Kallin, Demoulin, Nishida et al.: "Gab1 contributes to cytoskeletal reorganization and chemotaxis in response to platelet-derived growth factor." in: The Journal of biological chemistry, Vol. 279, Issue 17, pp. 17897-904, 2004 (PubMed).

Alternatives
Application Details Publications Variants back to top

Alternatives for antigen "GRB2-Associated Binding Protein 1 (GAB1)", type "Antibodies"
Hosts Rabbit (57), Mouse (2)
Reactivities Human (59), Mouse (Murine) (46), Rat (Rattus) (40), Cow (Bovine) (29), Dog (Canine) (28), Horse (Equine) (28), Pig (Porcine) (28), Chicken (10)
Applications Immunofluorescence (IF) (31), Western Blotting (WB) (26), Immunohistochemistry (IHC) (18), ELISA (17), Dot Blot (Dot) (3), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (3), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (3), Flow Cytometry (FACS) (1), Immunoelectron Microscopy (IEM) (1)
Conjugates Alexa Fluor 350 (3), Alexa Fluor 488 (3), Alexa Fluor 555 (3), Alexa Fluor 647 (3), PE,Cy5.5 (3), Biotin (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy7 (1)
Epitopes pTyr627 (12), pTyr659 (9), Tyr627 (2), Tyr659 (1), pTyr259 (1), pTyr407 (1)