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GDF15 antibody (Growth Differentiation Factor 15) (N-Term)

Details for Product anti-GDF15 Antibody No. ABIN966197, Supplier: Log in to see
Antigen
  • GDF-15
  • GDF15
  • MIC-1
  • MIC1
  • NAG-1
  • PDF
  • PLAB
  • PTGFB
  • SBF
Epitope
N-Term
79
52
17
16
15
13
11
7
6
5
5
5
4
3
2
2
2
1
1
1
1
1
1
1
Reactivity
Mouse (Murine), Rat (Rattus)
258
79
38
7
7
2
2
Host
Rabbit
228
28
19
5
Clonality
Polyclonal
Conjugate
This GDF15 antibody is un-conjugated
34
28
13
5
5
5
1
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (IHC)
237
204
79
25
23
12
11
6
5
4
1
1
Supplier
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Immunogen Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to N-terminal residues of mouse GDF-15 (Growth Differentiation factor 15)
Alternative Name GDF-15 (GDF15 Antibody Abstract)
Background GDF-15 (Growth Differentiation factor 15) is a transforming growth factor beta superfamily member induced following liver injury. GDF-15 is a homodimer and disulfide-linked by similarity. GDF-15 is secreted and highly expressed in liver. GDF-15 belongs to the TGF-beta family.
Synonyms: macrophage inhibiting cytokine-1(MIC-1)
Restrictions For Research Use only
Product cited in: Iguchi, Chrysovergis, Lee, Baek, Langenbach, Eling: "A reciprocal relationship exists between non-steroidal anti-inflammatory drug-activated gene-1 (NAG-1) and cyclooxygenase-2." in: Cancer letters, Vol. 282, Issue 2, pp. 152-8, 2009

Cekanova, Lee, Donnell, Sukhthankar, Eling, Fischer, Baek: "Nonsteroidal anti-inflammatory drug-activated gene-1 expression inhibits urethane-induced pulmonary tumorigenesis in transgenic mice." in: Cancer prevention research (Philadelphia, Pa.), Vol. 2, Issue 5, pp. 450-8, 2009

Ding, Mracek, Gonzalez-Muniesa, Kos, Wilding, Trayhurn, Bing: "Identification of macrophage inhibitory cytokine-1 in adipose tissue and its secretion as an adipokine by human adipocytes." in: Endocrinology, Vol. 150, Issue 4, pp. 1688-96, 2009

Zimmers, Jin, Gutierrez, Acosta, McKillop, Pierce, Koniaris: "Effect of in vivo loss of GDF-15 on hepatocellular carcinogenesis." in: Journal of cancer research and clinical oncology, Vol. 134, Issue 7, pp. 753-9, 2008

Noorali, Kurita, Woolcock, de Algara, Lo, Paralkar, Hoodless, Vielkind: "Dynamics of expression of growth differentiation factor 15 in normal and PIN development in the mouse." in: Differentiation; research in biological diversity, Vol. 75, Issue 4, pp. 325-36, 2007

Oxburgh, Chu, Michael, Robertson: "TGFbeta superfamily signals are required for morphogenesis of the kidney mesenchyme progenitor population." in: Development (Cambridge, England), Vol. 131, Issue 18, pp. 4593-605, 2004

Zambrowicz, Abuin, Ramirez-Solis, Richter, Piggott, BeltrandelRio, Buxton, Edwards, Finch, Friddle, Gupta, Hansen, Hu, Huang, Jaing, Key: "Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 100, Issue 24, pp. 14109-14, 2003