V-Erb-B2 erythroblastic Leukemia Viral Oncogene Homolog 2, Neuro/glioblastoma Derived Oncogene Homolog (Avian) (ERBB2) (pTyr877) antibody

Details for Product No. ABIN966276
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Antigen
Synonyms CD340, HER-2, HER-2/neu, HER2, MLN 19, NEU, NGL, TKR1, Erbb-2, Neu, c-erbB2, c-neu, mKIAA3023
Epitope
pTyr877
(64), (54), (52), (48), (42), (39), (35), (28), (26), (23), (21), (16), (12), (10), (10), (10), (10), (10), (9), (9), (9), (9), (9), (9), (8), (8), (8), (8), (8), (7), (7), (7), (7), (6), (6), (6), (6), (6), (6), (6), (6), (6), (6), (6), (6), (6), (6), (5), (5), (4), (4), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Human, Mouse (Murine), Rat (Rattus)
(826), (329), (217), (79), (60), (48), (36), (24), (6), (4), (4), (2)
Host
Rabbit
(691), (203), (18), (9), (5), (1)
Conjugate
Un-conjugated
(47), (37), (30), (24), (22), (20), (9), (9), (9), (9), (9), (9), (9), (9)
Application
Immunohistochemistry (IHC)
(492), (305), (237), (204), (182), (162), (106), (90), (60), (55), (46), (24), (15), (10), (5), (3), (1), (1), (1), (1)
Pubmed 3 references available
Quantity 100 μg
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Catalog No. ABIN966276
398.75 $
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Immunogen The antiserum was produced against synthesized phosphopeptide derived from human HER2 around the phosphorylation site of tyrosine 877 (T-E-YP-H-A).
Specificity HER2 (phospho-Tyr877) antibody detects endogenous levels of HER2 only when phosphorylated at tyrosine 877.
Alternative Name HER2
Application Notes WB: 1:500~1:1000
IHC: 1:50~1:100
Restrictions For Research Use only
Format Liquid
Concentration 100ug/100ul.
Buffer Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Product cited in: Qian, LeVea, Freeman et al.: "Heterodimerization of epidermal growth factor receptor and wild-type or kinase-deficient Neu: a mechanism of interreceptor kinase activation and transphosphorylation." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 91, Issue 4, pp. 1500-4, 1994 (PubMed).

Muthuswamy, Gilman, Brugge: "Controlled dimerization of ErbB receptors provides evidence for differential signaling by homo- and heterodimers." in: Molecular and cellular biology, Vol. 19, Issue 10, pp. 6845-57, 2000 (PubMed).

Dittadi, Gion: "More about: prognostic importance of low c-erbB2 expression in breast tumors." in: Journal of the National Cancer Institute, Vol. 92, Issue 17, pp. 1443-4, 2000 (PubMed).

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