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- Target See all Interferon gamma (IFNG) Antibodies
- Interferon gamma (IFNG)
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Reactivity
- Human
- Host
- Please inquire
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Clonality
- Monoclonal
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Conjugate
- This Interferon gamma antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA
- Specificity
- Ni-NTA purified recombinant human IFN-gamma expressed in E. Coli strain BL21 (DE3)
- Purification
- Antibodies are purified by protein A affinity chromatography
- Isotype
- IgG1
- Top Product
- Discover our top product IFNG Primary Antibody
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- Application Notes
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Dilution: Western Blot: 1:500-1,000
ELISA: Determining optimal working dilutions by titration test. - Restrictions
- For Research Use only
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- Storage
- -20 °C
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Regulation of human leukocyte antigen expression in human conjunctival epithelium." in: Investigative ophthalmology & visual science, Vol. 40, Issue 1, pp. 28-34, (1999) (PubMed).
: "
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Regulation of human leukocyte antigen expression in human conjunctival epithelium." in: Investigative ophthalmology & visual science, Vol. 40, Issue 1, pp. 28-34, (1999) (PubMed).
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- Target
- Interferon gamma (IFNG)
- Alternative Name
- IFN-Y (IFNG Products)
- Synonyms
- IFG antibody, IFI antibody, IFN-g antibody, Ifg antibody, IFNG2 antibody, IFN-gamma antibody, IFN-G antibody, IFNG antibody, IFNgamma antibody, TCRalpha antibody, INF-G antibody, ifng antibody, interferon gamma antibody, interferon, gamma 1-2 antibody, IFNG antibody, Ifng antibody, ifng1-2 antibody
- Background
- Interferon-gamma (IFN-gamma) is a pro-inflammatory cytokine that is central in host resistance to infection. It is mainly produced by natural killer cells and CD4+ and CD8+ T cells, its receptors are found on nearly all cells, where it activates diverse responses that enable potential host cells to prevent invasive infection by bacteria, parasites and viruses. Takayanagi et al. (2000) demonstrated that IFN-gamma strongly suppresses osteoclastogenesis by interfering with the RANKL (602642)-RANK (603499) signaling pathway. Tsubota et al. (1999) reported that this upregulation in Sjogren syndrome patients may be controlled by interferon-gamma through the activation of transcription factor NFKB.
- Gene ID
- 3458
- Pathways
- Interferon-gamma Pathway, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, ER-Nucleus Signaling, Regulation of Carbohydrate Metabolic Process, Protein targeting to Nucleus, Autophagy
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