Insulin-Like Growth Factor 1 (IGF1) (AA 80-96) antibody

Details for Product No. ABIN966342
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Antigen
Synonyms IGF-1, IGF-1L, IGF-1a, IGF-I, C730016P09Rik, Igf-1, Igf-I, IGF1A, IGFI, IGFIA, Npt2B, IGF-IB, IGF1
Epitope
AA 80-96
(7), (6), (6), (5), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Human, Rat (Rattus)
(141), (62), (42), (29), (26), (25), (4), (1), (1)
Host
(123), (31), (17), (5), (2)
Clonality
Polyclonal
Conjugate
Un-conjugated
(19), (4), (3), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1)
Application
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
(111), (90), (44), (25), (20), (20), (16), (16), (10), (8), (8), (7), (6), (4), (2), (1)
Pubmed 2 references available
Quantity 100 μg
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Catalog No. ABIN966342
330.00 $
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Immunogen A synthetic peptide corresponding to a sequence at the middle region of human IGF-1 (80-96 aa), different from the mouse and rat sequence by one amino acid.
Alternative Name IGF-1
Background Insulin-like growth factor 1 (IGF-1) also known as somatomedin C or mechano growth factor is a protein that in humans is encoded by the IGF1 gene. IGF-1 is a hormone similar in molecular structure to insulin. It plays an important role in childhood growth and continues to have anabolic effects in adults. A synthetic analog of IGF-1, mecasermin is used for the treatment of growth failure. IGF-1 consists of 70 amino acids in a single chain with three intramolecular disulfide bridges. IGF-1 has a molecular weight of 7649 daltons.Justice et al. (1990) placed the mouse IGF1 gene on chromosome 10.
Research Area Diabetes, Metabolism, Growth Factors
Application Notes WB: The detection limit for IGF-1 is approximately 2.5ng/lane under non-reducing and reducing conditions.
Restrictions For Research Use only
Reconstitution 0.2ml of distilled water will yield a concentration of 500µg/ml.
Buffer Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4
Preservative Thimerosal (Merthiolate), Sodium azide
Storage -20 °C
Product cited in: Höppener, de Pagter-Holthuizen, Geurts van Kessel et al.: "The human gene encoding insulin-like growth factor I is located on chromosome 12." in: Human genetics, Vol. 69, Issue 2, pp. 157-60, 1985 (PubMed).

Jansen, van Schaik, Ricker et al.: "Sequence of cDNA encoding human insulin-like growth factor I precursor." in: Nature, Vol. 306, Issue 5943, pp. 609-11, 1984 (PubMed).

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