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IGF1 antibody (AA 80-96)

IGF1 Reactivity: Human, Rat WB, IHC (p) Polyclonal unconjugated
Catalog No. ABIN966342
  • Target See all IGF1 Antibodies
    IGF1 (Insulin-Like Growth Factor 1 (IGF1))
    Binding Specificity
    • 18
    • 15
    • 15
    • 9
    • 8
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 80-96
    Reactivity
    • 151
    • 69
    • 60
    • 22
    • 16
    • 9
    • 7
    • 3
    • 2
    • 1
    Human, Rat
    Host
    Please inquire
    Clonality
    • 138
    • 53
    Polyclonal
    Conjugate
    • 95
    • 29
    • 13
    • 7
    • 5
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This IGF1 antibody is un-conjugated
    Application
    • 145
    • 77
    • 66
    • 57
    • 42
    • 30
    • 27
    • 26
    • 26
    • 20
    • 15
    • 14
    • 9
    • 8
    • 8
    • 7
    • 7
    • 6
    • 4
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Immunogen
    A synthetic peptide corresponding to a sequence at the middle region of human IGF-1 (80-96 aa), different from the mouse and rat sequence by one amino acid.
    Top Product
    Discover our top product IGF1 Primary Antibody
  • Application Notes
    WB: The detection limit for IGF-1 is approximately 2.5ng/lane under non-reducing and reducing conditions.
    Restrictions
    For Research Use only
  • Reconstitution
    0.2ml of distilled water will yield a concentration of 500µg/ml.
    Buffer
    Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4
    Preservative
    Thimerosal (Merthiolate), Sodium azide
    Storage
    -20 °C
  • Höppener, de Pagter-Holthuizen, Geurts van Kessel, Jansen, Kittur, Antonarakis, Lips, Sussenbach: "The human gene encoding insulin-like growth factor I is located on chromosome 12." in: Human genetics, Vol. 69, Issue 2, pp. 157-60, (1985) (PubMed).

    Jansen, van Schaik, Ricker, Bullock, Woods, Gabbay, Nussbaum, Sussenbach, Van den Brande: "Sequence of cDNA encoding human insulin-like growth factor I precursor." in: Nature, Vol. 306, Issue 5943, pp. 609-11, (1984) (PubMed).

  • Target
    IGF1 (Insulin-Like Growth Factor 1 (IGF1))
    Alternative Name
    IGF-1 (IGF1 Products)
    Synonyms
    IGF-I antibody, IGF1A antibody, IGFI antibody, C730016P09Rik antibody, Igf-1 antibody, Igf-I antibody, Npt2B antibody, IGF-1 antibody, IGFIA antibody, IGF-IB antibody, igf1 antibody, IGF-1L antibody, IGF-1a antibody, IGF1 antibody, igf-1 antibody, igf1-A antibody, igf1.S antibody, xigf1 antibody, insulin like growth factor 1 antibody, insulin-like growth factor 1 antibody, insulin-like growth factor I antibody, insulin like growth factor 1 L homeolog antibody, IGF1 antibody, Igf1 antibody, LOC100136741 antibody, igf1 antibody, LOC678666 antibody, igf1.L antibody, LOC104911603 antibody
    Background
    Insulin-like growth factor 1 (IGF-1) also known as somatomedin C or mechano growth factor is a protein that in humans is encoded by the IGF1 gene. IGF-1 is a hormone similar in molecular structure to insulin. It plays an important role in childhood growth and continues to have anabolic effects in adults. A synthetic analog of IGF-1, mecasermin is used for the treatment of growth failure. IGF-1 consists of 70 amino acids in a single chain with three intramolecular disulfide bridges. IGF-1 has a molecular weight of 7649 daltons.Justice et al. (1990) placed the mouse IGF1 gene on chromosome 10.
    Pathways
    RTK Signaling, Intracellular Steroid Hormone Receptor Signaling Pathway, Peptide Hormone Metabolism, Hormone Activity, Regulation of Intracellular Steroid Hormone Receptor Signaling, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Stem Cell Maintenance, Glycosaminoglycan Metabolic Process, Regulation of Carbohydrate Metabolic Process, Autophagy, Smooth Muscle Cell Migration, Activated T Cell Proliferation, Positive Regulation of fat Cell Differentiation
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