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IGF1 antibody (Insulin-Like Growth Factor 1) (AA 80-96)

Details for Product anti-IGF1 Antibody No. ABIN966342, Supplier: Login to see
Antigen
  • IGF-1
  • IGF-1L
  • IGF-1a
  • IGF-I
  • C730016P09Rik
  • Igf-1
  • Igf-I
  • IGF1A
  • IGFI
  • IGFIA
  • Npt2B
  • IGF-IB
  • IGF1
Alternatives
anti-Human IGF1 antibody for ELISA
Epitope
AA 80-96
16
14
13
13
11
10
6
5
5
4
4
4
3
3
3
2
1
1
1
1
1
1
1
1
1
1
Reactivity
Human, Rat (Rattus)
245
90
61
14
12
10
7
3
3
3
2
1
1
1
Host
179
80
37
8
2
2
1
Clonality
Polyclonal
Conjugate
This IGF1 antibody is un-conjugated
32
11
8
6
6
6
2
2
2
2
2
2
2
2
2
1
1
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
173
158
63
32
31
28
25
24
22
20
17
15
13
7
6
2
2
2
1
1
Supplier
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Immunogen A synthetic peptide corresponding to a sequence at the middle region of human IGF-1 (80-96 aa), different from the mouse and rat sequence by one amino acid.
Alternative Name IGF-1 (IGF1 Antibody Abstract)
Background Insulin-like growth factor 1 (IGF-1) also known as somatomedin C or mechano growth factor is a protein that in humans is encoded by the IGF1 gene. IGF-1 is a hormone similar in molecular structure to insulin. It plays an important role in childhood growth and continues to have anabolic effects in adults. A synthetic analog of IGF-1, mecasermin is used for the treatment of growth failure. IGF-1 consists of 70 amino acids in a single chain with three intramolecular disulfide bridges. IGF-1 has a molecular weight of 7649 daltons.Justice et al. (1990) placed the mouse IGF1 gene on chromosome 10.
Research Area Diabetes, Metabolism, Growth Factors
Pathways RTK Signaling
Application Notes WB: The detection limit for IGF-1 is approximately 2.5ng/lane under non-reducing and reducing conditions.
Restrictions For Research Use only
Reconstitution 0.2ml of distilled water will yield a concentration of 500µg/ml.
Buffer Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4
Preservative Thimerosal (Merthiolate), Sodium azide
Storage -20 °C
Product cited in: Jansen, van Schaik, Ricker et al.: "Sequence of cDNA encoding human insulin-like growth factor I precursor." in: Nature, Vol. 306, Issue 5943, pp. 609-11, 1984 (PubMed).

Höppener, de Pagter-Holthuizen, Geurts van Kessel et al.: "The human gene encoding insulin-like growth factor I is located on chromosome 12." in: Human genetics, Vol. 69, Issue 2, pp. 157-60, 1985 (PubMed).