anti-IGF1 antibody (Insulin-Like Growth Factor 1) (AA 80-96)

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Antigen
Synonyms IGF-1, IGF-1L, IGF-1a, IGF-I, C730016P09Rik, Igf-1, Igf-I, IGF1A, IGFI, IGFIA, Npt2B, IGF-IB, IGF1
Alternatives
Epitope
AA 80-96
(15), (13), (13), (11), (9), (8), (5), (4), (4), (3), (3), (3), (3), (3), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Human, Rat (Rattus)
(235), (91), (53), (11), (7), (7), (4), (4), (2), (1), (1), (1), (1), (1)
Host
(176), (74), (41), (8), (2), (1), (1)
Clonality
Polyclonal
Conjugate
This IGF1 antibody is un-conjugated
(38), (11), (8), (6), (6), (6), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1)
Application
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
(186), (166), (65), (37), (30), (28), (26), (22), (21), (18), (18), (16), (13), (7), (6), (3), (2), (2), (1), (1)
Pubmed 2 references available
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Quantity 100 μg
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Immunogen A synthetic peptide corresponding to a sequence at the middle region of human IGF-1 (80-96 aa), different from the mouse and rat sequence by one amino acid.
Alternative Name IGF-1 (IGF1 Antibody Abstract)
Background Insulin-like growth factor 1 (IGF-1) also known as somatomedin C or mechano growth factor is a protein that in humans is encoded by the IGF1 gene. IGF-1 is a hormone similar in molecular structure to insulin. It plays an important role in childhood growth and continues to have anabolic effects in adults. A synthetic analog of IGF-1, mecasermin is used for the treatment of growth failure. IGF-1 consists of 70 amino acids in a single chain with three intramolecular disulfide bridges. IGF-1 has a molecular weight of 7649 daltons.Justice et al. (1990) placed the mouse IGF1 gene on chromosome 10.
Research Area Diabetes, Metabolism, Growth Factors
Pathways RTK Signaling
Application Notes WB: The detection limit for IGF-1 is approximately 2.5ng/lane under non-reducing and reducing conditions.
Restrictions For Research Use only
Reconstitution 0.2ml of distilled water will yield a concentration of 500µg/ml.
Buffer Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4
Preservative Thimerosal (Merthiolate), Sodium azide
Storage -20 °C
Product cited in: Jansen, van Schaik, Ricker et al.: "Sequence of cDNA encoding human insulin-like growth factor I precursor." in: Nature, Vol. 306, Issue 5943, pp. 609-11, 1984 (PubMed).

Höppener, de Pagter-Holthuizen, Geurts van Kessel et al.: "The human gene encoding insulin-like growth factor I is located on chromosome 12." in: Human genetics, Vol. 69, Issue 2, pp. 157-60, 1985 (PubMed).

Catalog No. ABIN966342
$330.00
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