anti-NFKBIA antibody (Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells Inhibitor, alpha) (pSer32)

Details for Product anti-NFKBIA Antibody No. ABIN966363, Supplier: Login to see New
New
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Antigen
Synonyms AI462015, Nfkbi, IKBA, MAD-3, NFKBI, ECI-6/IKBA, RL/IF-1
Alternatives
Epitope
pSer32, pSer36
(50), (50), (38), (33), (28), (24), (24), (16), (15), (13), (13), (13), (7), (7), (5), (5), (4), (4), (3), (3), (3), (3), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Human, Mouse (Murine), Rat (Rattus)
(403), (192), (150), (10), (7), (4), (3), (3), (2), (1)
Host
Rabbit
(349), (61), (6), (2)
Conjugate
This NFKBIA antibody is un-conjugated
(14), (11), (9), (9), (6), (6), (4), (3), (3), (3), (3), (3), (3), (3), (3), (2)
Application
Immunohistochemistry (IHC)
(297), (146), (141), (75), (59), (58), (34), (18), (16), (16), (9), (6), (5), (3), (3), (2), (1), (1), (1), (1), (1)
Pubmed 4 references available
Supplier Login to see New
Supplier Product Number Login to see New
Quantity 100 μg
Options
Shipping to United States ( )
Availability Will be delivered in 5 to 7 Business Days
Immunogen The antiserum was produced against synthesized phosphopeptide derived from human IB- around the phosphorylation site of serine 32/36 (H-D-SP-G-L-D-SP -M-K).
Specificity IB- (phospho-Ser32/Ser36) antibody detects endogenous levels of IB- only when phosphorylated at serine 32/36.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Alternative Name IkB-alpha (NFKBIA Antibody Abstract)
Pathways NF-kappaB Signaling, TCR Signaling, TLR Signaling, Fc-epsilon Receptor Signaling Pathway
Application Notes IHC: 1:50-1:100.
Restrictions For Research Use only
Format Liquid
Concentration 100ug/100ul.
Buffer Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Product cited in: Hirao, Kong, Matsuoka et al.: "DNA damage-induced activation of p53 by the checkpoint kinase Chk2." in: Science (New York, N.Y.), Vol. 287, Issue 5459, pp. 1824-7, 2000 (PubMed).

Shieh, Taya, Prives: "DNA damage-inducible phosphorylation of p53 at N-terminal sites including a novel site, Ser20, requires tetramerization." in: The EMBO journal, Vol. 18, Issue 7, pp. 1815-23, 1999 (PubMed).

Tibbetts, Brumbaugh, Williams et al.: "A role for ATR in the DNA damage-induced phosphorylation of p53." in: Genes & development, Vol. 13, Issue 2, pp. 152-7, 1999 (PubMed).

Honda, Tanaka, Yasuda: "Oncoprotein MDM2 is a ubiquitin ligase E3 for tumor suppressor p53." in: FEBS letters, Vol. 420, Issue 1, pp. 25-7, 1998 (PubMed).

Catalog No. ABIN966363
$398.75
Plus shipping costs $45.00

Order hotline:

  • +1 877 302 8632
  • +1 888 205 9894 (TF)
Did you look for something else?