CHUK antibody (conserved Helix-Loop-Helix Ubiquitous Kinase) (pThr23)

Details for Product anti-CHUK Antibody No. ABIN966382, Supplier: Log in to see
Antigen
  • ikk
  • ikk1
  • ikka
  • ikkalpha
  • CHUK
  • IKBKA
  • IKK-alpha
  • IKK1
  • IKKA
  • NFKBIKA
  • TCF16
  • AI256658
  • Chuk1
  • Fbx24
  • Fbxo24
  • Ikka
  • zgc:56539
  • conserved helix-loop-helix ubiquitous kinase
  • chuk
  • CHUK
  • Chuk
Alternatives
anti-Human CHUK antibody for Immunofluorescence (fixed cells)
Epitope
pThr23
50
28
17
15
15
15
11
11
10
9
9
9
8
8
7
7
7
6
5
4
4
3
3
3
3
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
340
152
104
20
12
11
10
7
6
5
5
4
2
1
Host
Rabbit
262
81
12
1
Conjugate
This CHUK antibody is un-conjugated
15
11
11
9
8
8
3
3
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (IHC)
309
148
88
72
59
47
43
28
26
19
9
5
3
3
2
2
1
1
1
Options
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Immunogen The antiserum was produced against synthesized phosphopeptide derived from human IKK around the phosphorylation site of threonine 23 (L-G-TP-G-G).
Specificity IKK (phospho-Thr23) phosphorylated at threonine 23.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Alternative Name IKK alpha (CHUK Antibody Abstract)
Pathways PI3K-Akt Signaling, NF-kappaB Signaling, RTK Signaling, TCR Signaling, TLR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades
Application Notes WB: 1:500~1:1000
IHC: 1:50~1:100.
Restrictions For Research Use only
Format Liquid
Concentration 100ug/100ul.
Buffer Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Product cited in: Yuan, Feldman, Sun, Olashaw, Coppola, Sussman, Shelley, Nicosia, Cheng: "Inhibition of JNK by cellular stress- and tumor necrosis factor alpha-induced AKT2 through activation of the NF kappa B pathway in human epithelial Cells." in: The Journal of biological chemistry, Vol. 277, Issue 33, pp. 29973-82, 2002 (PubMed).

Ozes, Mayo, Gustin, Pfeffer, Pfeffer, Donner: "NF-kappaB activation by tumour necrosis factor requires the Akt serine-threonine kinase." in: Nature, Vol. 401, Issue 6748, pp. 82-5, 1999 (PubMed).