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IL1A antibody
IL1A
Reactivity: Human
WB, ELISA
Monoclonal
unconjugated
Product Details anti-IL1A Antibody
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Target
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IL1A
(Interleukin 1 alpha (IL1A))
Reactivity
All reactivities for IL1A antibodies
Human
Host
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Clonality
All clonalities for IL1A antibodies
Monoclonal
Conjugate
All conjugates for IL1A antibodies
This IL1A antibody is un-conjugated
Application
All applications for IL1A antibodies
Western Blotting (WB), ELISA
Specificity
Ni-NTA purified recombinant human IL-1 alpha, expressed in E. Coli strain BL21 (DE3).
Purification
Antibodies are purified by protein A affinity chromatography
Isotype
IgG2a
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Alternatives
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Application Details
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Application Notes
Dilution: Western Blot: 1:500-1,000 ELISA: Determining optimal working dilutions by titration test.
Restrictions
For Research Use only
Handling
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Storage
-20 °C
References for anti-IL1A antibody (ABIN966392)
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Du, Dodel, Eastwood, Bales, Gao, Lohmüller, Müller, Kurz, Zimmer, Evans, Hake, Gasser, Oertel, Griffin, Paul, Farlow : "Association of an interleukin 1 alpha polymorphism with Alzheimer's disease. " in: Neurology , Vol. 55 , Issue 4 , pp. 480-3 , (2000 ) (PubMed ).
Target Details for IL1A
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Target
IL1A
(Interleukin 1 alpha (IL1A))
Alternative Name
IL-1a (IL1A Products )
Synonyms
IL-1A antibody, IL1 antibody, IL1-ALPHA antibody, IL1F1 antibody, IL-6 antibody, Il-1a antibody, IL-1 alpha antibody, IL-1alpha antibody, L1A antibody, interleukin 1 alpha antibody, interleukin 6 antibody, IL1A antibody, IL6 antibody, Il1a antibody
Background
Interleukin-1alpha is a member of the interleukin 1 cytokine family. It is a pleiotropic cytokine involved in various immune responses, inflammatory processes, and hematopoiesis. This cytokine is produced by monocytes and macrophages as a proprotein, which is proteolytically processed and released in response to cell injury, and thus induces apoptosis. IL-1 alpha and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. It has been suggested that the polymorphism of these genes is associated with rheumatoid arthritis and Alzheimer's disease.
Gene ID
3552
Pathways
NF-kappaB Signaling , Autophagy , Cancer Immune Checkpoints
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