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Interleukin 6 antibody (IL6) (C-Term)

Details for Product anti-IL6 Antibody No. ABIN966395, Supplier: Log in to see
Antigen
  • Il-6
  • ILg6
  • Ifnb2
  • BSF2
  • HGF
  • HSF
  • IFNB2
  • IL-6
  • CHIL-6
  • il6
Epitope
C-Term
36
20
16
14
13
12
12
12
12
11
10
9
7
7
7
6
5
5
3
3
2
2
1
1
1
1
1
1
Reactivity
Rat (Rattus)
442
174
97
23
10
8
7
7
7
7
5
4
3
3
2
2
1
Host
Rabbit
341
205
153
37
9
7
2
Clonality
Polyclonal
Conjugate
This Interleukin 6 antibody is un-conjugated
102
37
17
17
11
6
3
3
3
3
3
3
3
3
2
2
2
1
1
1
1
Application
Western Blotting (WB)
473
445
111
107
100
62
44
43
39
32
28
25
22
17
14
13
12
8
6
5
4
4
4
4
4
4
3
2
2
2
1
1
1
1
1
Supplier
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Immunogen A synthetic peptide corresponding to a sequence at the C-terminal of rat IL6, different from the related mouse sequence by two amino acids.< br/>Immunogen was affinity purified.
Isotype IgG
Cross-Reactivity Mouse (Murine)
Cross-Reactivity (Details) No cross reactivity with other proteins.
Characteristics Rabbit IgG polyclonal antibody for Interleukin-6 ( IL6) detection. Tested with WB in Mouse, Rat.
Alternative Name Interleukin-6(IL-6) (IL6 Antibody Abstract)
Background Interleukin-6 (IL-6) is a protein that in humans is encoded by the IL6 gene. IL-6 is an interleukin that acts as both a pro-inflammatory and anti-inflammatory cytokine. It is secreted by T cells and macrophages to stimulate immune response to trauma, especially burns or other tissue damage leading to inflammation. IL-6 is one of the most important mediators of fever and of the acute phase response. IL-6 is also essential for hybridoma growth and is found in many supplemental cloning media such as briclone. Bowcock et al. (1988) assigned the IL6 gene to chromosome 7p21. By in situ hybridization and Southern blot analysis of mouse-human hybrid cell lines, Sutherland et al. (1988) mapped the IL6 gene to chromosome 7p15.
Pathways
Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 0.2 mL of distilled water will yield a concentration of 500 µg/mL.
Buffer Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
Preservative Sodium azide, Thimerosal (Merthiolate)
Handling Advice Avoid repeated freezing and thawing.
Storage -20 °C
Storage Comment At -20 °C for one year. After reconstitution, at 4 °C for one month. It can also be aliquotted and stored frozen at -20 °C for a longer time.
Product cited in: Ferguson-Smith, Chen, Newman et al.: "Regional localization of the interferon-beta 2/B-cell stimulatory factor 2/hepatocyte stimulating factor gene to human chromosome 7p15-p21." in: Genomics, Vol. 2, Issue 3, pp. 203-8, 1988 (PubMed).