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Insulin Receptor Substrate 1 (IRS1) antibody

Details for Product No. ABIN966417, Supplier: Log in to see
Antigen
  • irs1
  • irsu
  • IRS1
  • HIRS-1
  • G972R
  • IRS-1
  • IRS1IRM
  • irs-1
  • irs1-a
Alternatives
anti-Human Insulin Receptor Substrate 1 antibody for Enzyme Immunoassay
Reactivity
Human, Mouse (Murine), Rat (Rattus)
513
353
336
11
9
5
1
1
Host
Rabbit
510
30
Clonality
Polyclonal
Conjugate
Un-conjugated
13
12
11
11
11
10
10
10
10
10
10
10
2
1
1
1
Application
Immunohistochemistry (IHC)
313
214
137
112
102
79
30
30
12
4
2
1
Supplier
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Immunogen The antiserum was produced against synthesized non-phosphopeptide derived from human IRS-1 around the phosphorylation site of serine 307.
Specificity IRS-1 (Ab-307) antibody detects endogenous levels of total IRS-1 protein.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Alternative Name IRS-1 (IRS1 Antibody Abstract)
Pathways Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
Application Notes IHC: 1:50-1:100.
Restrictions For Research Use only
Format Liquid
Concentration 100ug/100ul.
Buffer Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Product cited in: Shoelson, Lee, Goldfine: "Inflammation and insulin resistance." in: The Journal of clinical investigation, Vol. 116, Issue 7, pp. 1793-801, 2006 (PubMed).

Tuncman, Hirosumi, Solinas et al.: "Functional in vivo interactions between JNK1 and JNK2 isoforms in obesity and insulin resistance." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 103, Issue 28, pp. 10741-6, 2006 (PubMed).

Steppan, Wang, Whiteman et al.: "Activation of SOCS-3 by resistin." in: Molecular and cellular biology, Vol. 25, Issue 4, pp. 1569-75, 2005 (PubMed).

Frolov, Drozdova, Kazanskaia et al.: "[The synchronization and desynchronization of the" in: Biulleten' eksperimental'noĭ biologii i meditsiny, Vol. 116, Issue 7, pp. 17-9, 1993 (PubMed).