You are viewing an incomplete version of our website. Please click to reload the website as full version.

Insulin Receptor Substrate 1 (IRS1) antibody

Details for Product No. ABIN966417, Supplier: Log in to see
Antigen
  • G972R
  • HIRS-1
  • irs-1
  • IRS-1
  • irs1
  • IRS1
  • irs1-a
  • IRS1IRM
  • irsu
Alternatives
anti-Human Insulin Receptor Substrate 1 antibody for Enzyme Immunoassay
Reactivity
Human, Mouse (Murine), Rat (Rattus)
506
351
334
11
8
4
1
Host
Rabbit
503
30
Clonality
Polyclonal
Conjugate
Un-conjugated
13
11
11
11
10
10
10
10
10
10
10
10
2
1
1
1
Application
Immunohistochemistry (IHC)
308
212
137
110
102
79
30
29
12
4
2
1
Supplier
Log in to see
Supplier Product No.
Log in to see
Request

Get this product for free

It's quick and easy to submit your validation proposal. I want to validate this product

Learn more

Immunogen The antiserum was produced against synthesized non-phosphopeptide derived from human IRS-1 around the phosphorylation site of serine 307.
Specificity IRS-1 (Ab-307) antibody detects endogenous levels of total IRS-1 protein.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Alternative Name IRS-1 (IRS1 Antibody Abstract)
Pathways Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
Application Notes IHC: 1:50-1:100.
Restrictions For Research Use only
Format Liquid
Concentration 100ug/100ul.
Buffer Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Product cited in: Tuncman, Hirosumi, Solinas, Chang, Karin, Hotamisligil: "Functional in vivo interactions between JNK1 and JNK2 isoforms in obesity and insulin resistance." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 103, Issue 28, pp. 10741-6, 2006

Shoelson, Lee, Goldfine: "Inflammation and insulin resistance." in: The Journal of clinical investigation, Vol. 116, Issue 7, pp. 1793-801, 2006

Steppan, Wang, Whiteman, Birnbaum, Lazar: "Activation of SOCS-3 by resistin." in: Molecular and cellular biology, Vol. 25, Issue 4, pp. 1569-75, 2005

Frolov, Drozdova, Kazanskaia, Ramdavon: "[The synchronization and desynchronization of the" in: Biulleten' eksperimental'noĭ biologii i meditsiny, Vol. 116, Issue 7, pp. 17-9, 1993