Insulin Receptor Substrate 1 (IRS1) antibody

Details for Product No. ABIN966417, Supplier: Log in to see
Antigen
  • irs1
  • irsu
  • IRS1
  • HIRS-1
  • G972R
  • IRS-1
  • IRS1IRM
  • irs-1
  • irs1-a
  • insulin receptor substrate 2
  • insulin receptor substrate 1
  • irs2
  • IRS1
  • Irs1
  • irs1
Alternatives
anti-Human Insulin Receptor Substrate 1 antibody for Enzyme Immunoassay
Reactivity
Human, Mouse (Murine), Rat (Rattus)
570
431
409
19
16
6
5
4
4
1
1
Host
Rabbit
565
32
Clonality
Polyclonal
Conjugate
Un-conjugated
13
11
11
11
10
10
10
10
10
10
10
10
10
10
2
2
1
1
Application
Immunohistochemistry (IHC)
342
216
146
144
130
105
31
28
14
12
4
3
2
Options
Supplier
Log in to see
Supplier Product No.
Log in to see
Immunogen The antiserum was produced against synthesized non-phosphopeptide derived from human IRS-1 around the phosphorylation site of serine 307.
Specificity IRS-1 (Ab-307) antibody detects endogenous levels of total IRS-1 protein.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Alternative Name IRS-1 (IRS1 Antibody Abstract)
Pathways Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Positive Regulation of Peptide Hormone Secretion, Hormone Transport, Negative Regulation of Hormone Secretion, Response to Growth Hormone Stimulus, Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process
Application Notes IHC: 1:50-1:100.
Restrictions For Research Use only
Format Liquid
Concentration 100ug/100ul.
Buffer Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Product cited in: Tuncman, Hirosumi, Solinas, Chang, Karin, Hotamisligil: "Functional in vivo interactions between JNK1 and JNK2 isoforms in obesity and insulin resistance." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 103, Issue 28, pp. 10741-6, 2006 (PubMed).

Shoelson, Lee, Goldfine: "Inflammation and insulin resistance." in: The Journal of clinical investigation, Vol. 116, Issue 7, pp. 1793-801, 2006 (PubMed).

Steppan, Wang, Whiteman, Birnbaum, Lazar: "Activation of SOCS-3 by resistin." in: Molecular and cellular biology, Vol. 25, Issue 4, pp. 1569-75, 2005 (PubMed).

Frolov, Drozdova, Kazanskaia, Ramdavon: "[The synchronization and desynchronization of the" in: Biulleten' eksperimental'noĭ biologii i meditsiny, Vol. 116, Issue 7, pp. 17-9, 1993 (PubMed).

Did you look for something else?