Janus Kinase 2 (JAK2) (pTyr221) antibody

Details for Product No. ABIN966431
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Antigen
Synonyms JAK2bCA, jak2, JTK10, THCYT3, AI504024, C81284, Fd17, JAK-2
Epitope
pTyr221
(41), (28), (16), (13), (12), (10), (10), (4), (4), (4), (4), (3), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Human, Mouse (Murine), Rat (Rattus)
(211), (158), (152), (38), (25), (24), (12), (2), (2), (1), (1)
Host
Rabbit
(213), (11), (2)
Conjugate
Un-conjugated
(8), (4), (4), (3), (3), (3), (3), (3), (3), (3), (3), (1), (1)
Application
Immunohistochemistry (IHC)
(149), (94), (91), (35), (30), (19), (17), (11), (6), (5), (3), (3), (2)
Pubmed 2 references available
Quantity 100 μg
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Catalog No. ABIN966431
398.75 $
Plus shipping costs $45.00

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  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Immunogen The antiserum was produced against synthesized phosphopeptide derived from human JAK2 around the phosphorylation site of tyrosine 221 (Q-D-YP-H-I).
Specificity JAK2 (phospho-Tyr221) antibody phosphorylated at tyrosine 221.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Alternative Name JAK2
Research Area Signaling, Cytokines, Receptors, Kinases/Phosphatases
Application Notes IHC: 1:50-1:100.
Restrictions For Research Use only
Format Liquid
Concentration 100ug/100ul.
Buffer Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Product cited in: Argetsinger, Kouadio, Steen et al.: "Autophosphorylation of JAK2 on tyrosines 221 and 570 regulates its activity." in: Molecular and cellular biology, Vol. 24, Issue 11, pp. 4955-67, 2004 (PubMed).

Feener, Rosario, Dunn et al.: "Tyrosine phosphorylation of Jak2 in the JH2 domain inhibits cytokine signaling." in: Molecular and cellular biology, Vol. 24, Issue 11, pp. 4968-78, 2004 (PubMed).

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