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KLHL22 antibody

KLHL22 Reactivity: Human WB, IF Host: Mouse Monoclonal 7B10 unconjugated
Catalog No. ABIN966459
  • Target See all KLHL22 Antibodies
    KLHL22 (Kelch-Like 22 (KLHL22))
    Reactivity
    • 33
    • 33
    • 17
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human
    Host
    • 38
    • 10
    Mouse
    Clonality
    • 39
    • 9
    Monoclonal
    Conjugate
    • 13
    • 5
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This KLHL22 antibody is un-conjugated
    Application
    • 37
    • 22
    • 13
    • 13
    • 4
    • 3
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF)
    Purification
    Ascitic fluid
    Immunogen
    Purified recombinant fragment of human KLHL22 expressed in E. Coli.
    Clone
    7B10
    Isotype
    IgG1
    Top Product
    Discover our top product KLHL22 Primary Antibody
  • Application Notes
    Western Bloting: 1/500 - 1/2000.
    Immunofluorescence: 1/200 - 1/1000.
    ELISA: Propose dilution 1/10000.
    Not yet tested in other applications.
    Determining optimal working dilutions by titration test.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C
  • Maruyama, Sugano: "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides." in: Gene, Vol. 138, Issue 1-2, pp. 171-4, (1994) (PubMed).

  • Target
    KLHL22 (Kelch-Like 22 (KLHL22))
    Alternative Name
    KLHL22 (KLHL22 Products)
    Synonyms
    2610318I18Rik antibody, Kelchl antibody, KELCHL antibody, RGD1306288 antibody, kelch-like 22 antibody, kelch like family member 22 antibody, kelch-like family member 22 antibody, Klhl22 antibody, KLHL22 antibody
    Background
    KLHL22 (kelch-like protein 22) is a 634 amino acid protein that is related to the Drosophilakelch protein, which is required to maintain Actin organization in ovarian ring canals. Mutations affecting Kelch function result in the failure of Kelch to associate with the ring canals and subsequent female sterility. Human KLHL22 protein contains six kelch repeats and one BTB (POZ) domain. The BTB (Broad-Complex, Tramtrack and Bric a brac) domain, also known as the POZ (Poxvirus and Zinc finger) domain, is an N-terminal homodimerization domain that contains multiple copies of kelch repeats and/or C2H2-type zinc fingers. Proteins that contain BTB domains are thought to be involved in transcriptional regulation via control of chromatin structure and function. There are two isoforms of KLHL22 that are produced as a result of alternative splicing events.
    Synonyms: KELCHL, KLHL22
    Molecular Weight
    72kDa
    Gene ID
    84861
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