LIM Domain Kinase 2 (LIMK2) antibody

Details for Product No. ABIN966487
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Antigen
Synonyms xlimk2, zgc:91990, wu:fa97c09, wu:fk73e11, LIMK2, Limk2b, Link2, LIMK, 9430059K01, A930024P04Rik, C85310, Limk2a
Reactivity
Human, Mouse (Murine), Rat (Rattus)
(109), (68), (68), (1)
Host
Rabbit
(101), (5), (3)
Clonality
Polyclonal
Application
Immunohistochemistry (IHC)
(100), (51), (50), (31), (12), (12), (2), (1), (1), (1)
Pubmed 3 references available
Quantity 100 μg
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Catalog No. ABIN966487
398.75 $
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Immunogen The antiserum was produced against synthesized non-phosphopeptide derived from human LIMK2 around the phosphorylation site of threonine 505 (R-Y-TP-V-V).
Specificity LIMK2 (Ab-505) Antibody detects endogenous levels of total LIMK2 protein.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Alternative Name LIMK2
Application Notes WB: 1:500~1:1000.
Restrictions For Research Use only
Format Liquid
Concentration 100ug/100ul.
Buffer Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Product cited in: Edwards, Sanders, Bokoch et al.: "Activation of LIM-kinase by Pak1 couples Rac/Cdc42 GTPase signalling to actin cytoskeletal dynamics." in: Nature cell biology, Vol. 1, Issue 5, pp. 253-9, 1999 (PubMed).

Ohashi, Nagata, Maekawa et al.: "Rho-associated kinase ROCK activates LIM-kinase 1 by phosphorylation at threonine 508 within the activation loop." in: The Journal of biological chemistry, Vol. 275, Issue 5, pp. 3577-82, 2000 (PubMed).

Soosairajah, Maiti, Wiggan et al.: "Interplay between components of a novel LIM kinase-slingshot phosphatase complex regulates cofilin." in: The EMBO journal, Vol. 24, Issue 3, pp. 473-86, 2005 (PubMed).

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