Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

MEK1 antibody (C-Term)

MAP2K1 Reactivity: Human, Rat WB, IHC (p), ICC Polyclonal unconjugated
Catalog No. ABIN966512
  • Target See all MEK1 (MAP2K1) Antibodies
    MEK1 (MAP2K1) (Mitogen-Activated Protein Kinase Kinase 1 (MAP2K1))
    Binding Specificity
    • 42
    • 28
    • 28
    • 22
    • 22
    • 20
    • 19
    • 19
    • 18
    • 16
    • 15
    • 14
    • 12
    • 11
    • 10
    • 8
    • 7
    • 7
    • 6
    • 5
    • 5
    • 5
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 353-367, C-Term
    Reactivity
    • 364
    • 195
    • 194
    • 33
    • 30
    • 18
    • 12
    • 12
    • 12
    • 10
    • 7
    • 6
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Rat
    Host
    Please inquire
    Clonality
    • 293
    • 75
    Polyclonal
    Conjugate
    • 177
    • 25
    • 22
    • 17
    • 12
    • 12
    • 12
    • 12
    • 12
    • 12
    • 11
    • 10
    • 5
    • 5
    • 5
    • 5
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This MEK1 antibody is un-conjugated
    Application
    • 243
    • 124
    • 101
    • 68
    • 66
    • 47
    • 33
    • 30
    • 25
    • 15
    • 11
    • 10
    • 7
    • 5
    • 3
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)
    Immunogen
    A synthetic peptide corresponding to a sequence at the C-terminal of human MAP2K1 (353-367aa), identical to the related mouse and rat sequence.
    Top Product
    Discover our top product MAP2K1 Primary Antibody
  • Restrictions
    For Research Use only
  • Reconstitution
    0.2ml of distilled water will yield a concentration of 500µg/ml.
    Buffer
    Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4
    Preservative
    Thimerosal (Merthiolate), Sodium azide
    Storage
    -20 °C
  • Rampoldi, Zimbello, Bortoluzzi, Tiso, Valle, Lanfranchi, Danieli: "Chromosomal localization of four MAPK signaling cascade genes: MEK1, MEK3, MEK4 and MEKK5." in: Cytogenetics and cell genetics, Vol. 78, Issue 3-4, pp. 301-3, (1998) (PubMed).

    Zheng, Guan: "Cloning and characterization of two distinct human extracellular signal-regulated kinase activator kinases, MEK1 and MEK2." in: The Journal of biological chemistry, Vol. 268, Issue 15, pp. 11435-9, (1993) (PubMed).

  • Target
    MEK1 (MAP2K1) (Mitogen-Activated Protein Kinase Kinase 1 (MAP2K1))
    Alternative Name
    MAP2K1 (MAP2K1 Products)
    Synonyms
    Mek1 antibody, CFC3 antibody, MAPKK1 antibody, MEK1 antibody, MKK1 antibody, PRKMK1 antibody, MEKK1 antibody, Prkmk1 antibody, mek-2 antibody, si:ch211-242m18.2 antibody, wu:fj56a12 antibody, wu:fj61b01 antibody, zgc:56557 antibody, ATMEK1 antibody, F20B18.180 antibody, F20B18_180 antibody, MAP kinase/ ERK kinase 1 antibody, MITOGEN ACTIVATED PROTEIN KINASE KINASE antibody, MITOGEN ACTIVATED PROTEIN KINASE KINASE 1 antibody, NMAPKK antibody, MEK antibody, mitogen activated protein kinase kinase 1 antibody, mitogen-activated protein kinase kinase 1 antibody, mitogen-activated protein kinase kinase 1 L homeolog antibody, MAP kinase/ ERK kinase 1 antibody, Map2k1 antibody, MAP2K1 antibody, map2k1.L antibody, map2k1 antibody, MEK1 antibody
    Background
    Dual specificity mitogen-activated protein kinase kinase 1 is an enzyme that in humans is encoded by the MAP2K1 gene. The protein encoded by this gene is a member of the dual specificity protein kinase family, which acts as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This protein kinase lies upstream of MAP kinases and stimulates the enzymatic activity of MAP kinases upon activation by a wide variety of extra- and intracellular signals. As an essential component of the MAP kinase signal transduction pathway, this kinase is involved in many cellular processes such as proliferation, differentiation, transcription regulation and development. Rampoldi et al. (1997) localized the MAP2K1 gene to 15q22.1-q22.33.
    Pathways
    MAPK Signaling, RTK Signaling, Interferon-gamma Pathway, Fc-epsilon Receptor Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades, Autophagy, Signaling of Hepatocyte Growth Factor Receptor, BCR Signaling
You are here:
Support