Microtubule-Associated Protein 4 (MAP4) (Isoform 4), (pSer1046) antibody

Details for Product No. ABIN966517
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Antigen
Synonyms XMAP4, mtap4, AA407148, MAP-4, Mtap-4, Mtap4
Epitope
Isoform 4, pSer1046
(13), (12), (12), (4), (3), (3), (2), (2), (1), (1), (1), (1), (1), (1)
Reactivity
Mouse (Murine)
(78), (63), (62)
Host
Rabbit
(74), (3)
Clonality
Polyclonal
Conjugate
Un-conjugated
(4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4)
Application
(40), (26), (21), (18), (13), (10), (3), (1), (1)
Pubmed 6 references available
Quantity 0.1 mg
Options
Shipping to United States ( )
Availability Will be delivered in 5 to 7 Business Days
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Immunogen Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to C-terminal residues of human MAP4 (microtubule-associated protein 4 isoform 4)
Alternative Name MAP4 (MAP4 Antibody Abstract)
Background MAP4 (microtubule-associated protein 4 isoform 4) is a major non-neuronal microtubule-associated protein. This protein contains a domain similar to the microtubule-binding domains of neuronal microtubule-associated protein (MAP2) and microtubule-associated protein tau (MAPT/TAU). This protein promotes microtubule assembly, and has been shown to counteract destabilization of interphase microtubule catastrophe promotion. Cyclin B was found to interact with this protein, which targets cell division cycle 2 (CDC2) kinase to microtubules. The phosphorylation of this protein affects microtubule properties and cell cycle progression. Multiple transcript variants encoding different isoforms have been found for this gene.
Synonyms: DKFZp779A1753, MGC8617
Restrictions For Research Use only
Product cited in: Wu, Ma, Brown et al.: "Systematic identification of SH3 domain-mediated human protein-protein interactions by peptide array target screening." in: Proteomics, Vol. 7, Issue 11, pp. 1775-85, 2007 (PubMed).

Olsen, Blagoev, Gnad et al.: "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks." in: Cell, Vol. 127, Issue 3, pp. 635-48, 2006 (PubMed).

Beausoleil, Villén, Gerber et al.: "A probability-based approach for high-throughput protein phosphorylation analysis and site localization." in: Nature biotechnology, Vol. 24, Issue 10, pp. 1285-92, 2006 (PubMed).

Ookata, Hisanaga, Bulinski et al.: "Cyclin B interaction with microtubule-associated protein 4 (MAP4) targets p34cdc2 kinase to microtubules and is a potential regulator of M-phase microtubule dynamics." in: The Journal of cell biology, Vol. 128, Issue 5, pp. 849-62, 1995 (PubMed).

Chapin, Lue, Yu et al.: "Differential expression of alternatively spliced forms of MAP4: a repertoire of structurally different microtubule-binding domains." in: Biochemistry, Vol. 34, Issue 7, pp. 2289-301, 1995 (PubMed).

West, Tenbarge, Olmsted: "A model for microtubule-associated protein 4 structure. Domains defined by comparisons of human, mouse, and bovine sequences." in: The Journal of biological chemistry, Vol. 266, Issue 32, pp. 21886-96, 1991 (PubMed).

Validation Images
Catalog No. ABIN966517
466.13 $
Plus shipping costs $45.00
Quantity
Price
0.1 mg
466.13 $

Order hotline:

  • +1 877 302 8632
  • +1 888 205 9894 (TF)
Did you look for something else?