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Myelin Expression Factor 2 (MYEF2) (C-Term), (pSer454) antibody

Details for Product No. ABIN966552, Supplier: Log in to see
Antigen
  • MYEF2
  • mef-2
  • mst156
  • mstp156
  • hst18564
  • 9430071B01
  • mKIAA1341
  • zgc:123351
  • zgc:152722
  • HsT18564
  • MEF-2
  • MST156
  • MSTP156
Epitope
C-Term, pSer454
4
3
2
2
2
1
1
1
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
34
16
16
3
3
3
2
2
2
Host
Rabbit
37
Clonality
Polyclonal
Conjugate
Un-conjugated
2
2
2
Application
Immunohistochemistry (IHC)
24
20
16
8
3
3
1
Supplier
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Immunogen Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to C-terminal residues of human MEF2 (myocyte enhancer factor 2)
Alternative Name MEF2 (MYEF2 Antibody Abstract)
Background The process of differentiation from mesodermal precursor cells to myoblasts has led to the discovery of a variety of tissue-specific factors that regulate muscle gene expression. A family of DNA binding regulatory proteins is the myocyte-specific enhancer factor-2 (MEF2) family. Each of these proteins binds to the MEF2 target DNA sequence present in the regulatory regions of many muscle-specific genes. The MEF2 genes are members of the MADS gene family, a family that also includes several homeotic genes and other transcription factors, all of which share a conserved DNAbinding domain.
Restrictions For Research Use only
Product cited in: Zhao, Geng, Ge et al.: "Activation of ERK5 in angiotensin II-induced hypertrophy of human aortic smooth muscle cells." in: Molecular and cellular biochemistry, Vol. 322, Issue 1-2, pp. 171-8, 2009 (PubMed).

Vega, Salas, Milne et al.: "Evaluating new candidate SNPs as low penetrance risk factors in sporadic breast cancer: a two-stage Spanish case-control study." in: Gynecologic oncology, Vol. 112, Issue 1, pp. 210-4, 2008 (PubMed).

Molkentin, Li, Olson: "Phosphorylation of the MADS-Box transcription factor MEF2C enhances its DNA binding activity." in: The Journal of biological chemistry, Vol. 271, Issue 29, pp. 17199-204, 1996 (PubMed).

Krainc, Haas, Ward et al.: "Assignment of human myocyte-specific enhancer binding factor 2C (hMEF2C) to human chromosome 5q14 and evidence that MEF2C is evolutionarily conserved." in: Genomics, Vol. 29, Issue 3, pp. 809-11, 1996 (PubMed).

Hobson, Krahe, Garcia et al.: "Regional chromosomal assignments for four members of the MADS domain transcription enhancer factor 2 (MEF2) gene family to human chromosomes 15q26, 19p12, 5q14, and 1q12-q23." in: Genomics, Vol. 29, Issue 3, pp. 704-11, 1996 (PubMed).

McDermott, Cardoso, Yu et al.: "hMEF2C gene encodes skeletal muscle- and brain-specific transcription factors." in: Molecular and cellular biology, Vol. 13, Issue 4, pp. 2564-77, 1993 (PubMed).