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Details for Product No. ABIN966567

Neurofibromin 2 (NF2) (pSer518) antibody

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Antigen
Synonyms NF2a, nf2, ACN, SCH, BANF, merlin, zgc:194620, zgc:194631, NF2
Epitope
»Alternatives pSer518
Reactivity
»Alternatives Human, Mouse (Murine), Rat (Rattus)
Host
»Alternatives Rabbit
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives Immunohistochemistry (IHC)
Pubmed 3 references available
Catalog no. ABIN966567
Quantity 100 µg
Price
385.00 $   Plus shipping costs $45.00
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Availability Will be delivered in 5 to 7 Business Days
Immunogen The antiserum was produced against synthesized phosphopeptide derived from human Merlin around the phosphorylation site of serine 518 (R-L-SP-M-E).
Specificity Merlin (phospho-Ser518) antibody detects endogenous levels of Merlin only when phosphorylated at serine 518.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using nonphosphopeptide corresponding to the phosphorylation site.
Alternative Name Merlin
Application Notes WB: 1:500~1:1000.
Restrictions For Research Use only
Format Liquid
Concentration 100ug/100ul.
Buffer Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol
Preservative Sodium azide
Storage -20 °C
Product cited in: Böhni, Hemmi, Aguet: "Signaling steps involving the cytoplasmic domain of the interferon-gamma receptor alpha-subunit are not species-specific." in: The Journal of biological chemistry, Vol. 269, Issue 20, pp. 14541-5, 1994 (PubMed).

Ratner, Bryan, Weber et al.: "Cystic fibrosis pathogens activate Ca2+-dependent mitogen-activated protein kinase signaling pathways in airway epithelial cells." in: The Journal of biological chemistry, Vol. 276, Issue 22, pp. 19267-75, 2001 (PubMed).

Xiao, Gallagher, Shetler et al.: "The NF2 tumor suppressor gene product, merlin, inhibits cell proliferation and cell cycle progression by repressing cyclin D1 expression." in: Molecular and cellular biology, Vol. 25, Issue 6, pp. 2384-94, 2005 (PubMed).

Alternatives for antigen "Neurofibromin 2 (NF2)", type "Antibodies"
Hosts (95), (8), (3)
Reactivities (98), (72), (66), (25), (24), (24), (24), (7), (1)
Applications (78), (52), (20), (19), (17), (15), (5), (4), (2), (1), (1)
Conjugates (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2)
Epitopes (37), (8), (7), (5), (4), (4), (2), (1), (1), (1), (1), (1)
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