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|+1 404 474 4654|
|+1 888 205 9894 (TF)|
Met Proto-Oncogene (Hepatocyte Growth Factor Receptor) (MET) (pTyr1349) antibody
|Synonyms||SF, HGFB, HPTA, F-TCF, DFNB39, NK1, NK2, HGF/SF, SF/HGF, C230052L06Rik, HGF, CACNA2D1, MET|
Human, Mouse (Murine), Rat (Rattus)
Alternatives Immunohistochemistry (IHC)
|4 references available|
|Quantity||100ug (100ug/100ul.) (Variants)|
|Price||385.00 $ Plus shipping costs $45.00|
|Availability||Will be delivered in 5 to 7 Business Days|
|Immunogen||The antiserum was produced against synthesized phosphopeptide derived from human Met around the phosphorylation site of tyrosine 1349 (E-H-YP-V-H).|
|Specificity||Met (phospho-Tyr1349) antibody detects endogenous levels of Met only when phosphorylated at tyrosine 1349.|
|Application Notes||WB: 1:500~1:1000|
|Purification||The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.|
|Buffer||Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol|
|Preservative||0.02% Sodium Azide|
|Storage||Store at -20°C/1 year.|
|Restrictions||For Research Use only|
Ponzetto, Bardelli, Maina et al.: "A novel recognition motif for phosphatidylinositol 3-kinase binding mediates its association with the hepatocyte growth factor/scatter factor receptor." in: Molecular and cellular biology, Vol. 13, Issue 8, pp. 4600-8, 1993 (PubMed).
Plopper, McNamee, Dike et al.: "Convergence of integrin and growth factor receptor signaling pathways within the focal adhesion complex." in: Molecular biology of the cell, Vol. 6, Issue 10, pp. 1349-65, 1996 (PubMed).
Fan, Ma, Gao et al.: "The multisubstrate adapter Gab1 regulates hepatocyte growth factor (scatter factor)-c-Met signaling for cell survival and DNA repair." in: Molecular and cellular biology, Vol. 21, Issue 15, pp. 4968-84, 2001 (PubMed).
Schiering, Knapp, Marconi et al.: "Crystal structure of the tyrosine kinase domain of the hepatocyte growth factor receptor c-Met and its complex with the microbial alkaloid K-252a." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 100, Issue 22, pp. 12654-9, 2003 (PubMed).