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Met Proto-Oncogene (Hepatocyte Growth Factor Receptor) (MET) (pTyr1349) antibody

Antigen

Met Proto-Oncogene (Hepatocyte Growth Factor Receptor) (MET)
Synonyms SF, HGFB, HPTA, F-TCF, DFNB39, NK1, NK2, HGF/SF, SF/HGF, C230052L06Rik, HGF, CACNA2D1, MET
Binding Site
Alternatives

pTyr1349
Host
Alternatives

Rabbit
Reactivity
Alternatives

Human, Mouse (Murine), Rat (Rattus)
Conjugate
Alternatives Un-conjugated
Application
Alternatives Immunohistochemistry (IHC)
4 references available
Catalog no. ABIN966570
Quantity 100ug  (100ug/100ul.)  (Variants)
Price 385.00 $   Plus shipping costs $45.00
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Additional Information
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Alternative name Met
Immunogen The antiserum was produced against synthesized phosphopeptide derived from human Met around the phosphorylation site of tyrosine 1349 (E-H-YP-V-H).
Specificity Met (phospho-Tyr1349) antibody detects endogenous levels of Met only when phosphorylated at tyrosine 1349.

Application Details
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Application Notes WB: 1:500~1:1000
Concentration 100ug/100ul.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Buffer Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol
Preservative 0.02% Sodium Azide
Storage Store at -20°C/1 year.
Restrictions For Research Use only

Publications
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Product Ponzetto, Bardelli, Maina et al.: "A novel recognition motif for phosphatidylinositol 3-kinase binding mediates its association with the hepatocyte growth factor/scatter factor receptor." in: Molecular and cellular biology, Vol. 13, Issue 8, pp. 4600-8, 1993 (PubMed).

Plopper, McNamee, Dike et al.: "Convergence of integrin and growth factor receptor signaling pathways within the focal adhesion complex." in: Molecular biology of the cell, Vol. 6, Issue 10, pp. 1349-65, 1996 (PubMed).

Fan, Ma, Gao et al.: "The multisubstrate adapter Gab1 regulates hepatocyte growth factor (scatter factor)-c-Met signaling for cell survival and DNA repair." in: Molecular and cellular biology, Vol. 21, Issue 15, pp. 4968-84, 2001 (PubMed).

Schiering, Knapp, Marconi et al.: "Crystal structure of the tyrosine kinase domain of the hepatocyte growth factor receptor c-Met and its complex with the microbial alkaloid K-252a." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 100, Issue 22, pp. 12654-9, 2003 (PubMed).

Alternatives
Application Details Publications Variants back to top

Alternatives for antigen "Met Proto-Oncogene (Hepatocyte Growth Factor Receptor) (MET)", type "Antibodies"
Hosts Rabbit (124), Mouse (17), Rat (Rattus) (1)
Reactivities Human (138), Mouse (Murine) (83), Rat (Rattus) (72), Cow (Bovine) (16), Dog (Canine) (16), Pig (Porcine) (15), Sheep (Ovine) (15), Guinea Pig (10), Horse (Equine) (10), Chicken (6), Cat (Feline) (1)
Applications Western Blotting (WB) (88), ELISA (42), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (33), Immunofluorescence (IF) (31), Immunohistochemistry (IHC) (15), Immunocytochemistry (ICC) (4), Immunoprecipitation (IP) (4), Dot Blot (Dot) (2), Immunohistochemistry (Frozen Sections) (IHC (fro)) (2), Cell-ELISA (cELISA) (1), Flow Cytometry (FACS) (1), Fluorescence Microscopy (FM) (1)
Conjugates Alexa Fluor 350 (4), Alexa Fluor 488 (4), Alexa Fluor 555 (4), Alexa Fluor 647 (4), PE,Cy5.5 (4)
Epitopes pTyr1349 (12), pTyr1234 (7), pTyr1003 (6), pTyr1235,pTyr1234 (5), pTyr1365 (4), C-Term (3), Internal Region (3), Tyr1234 (2), Tyr1349 (2), pTyr1234,pTyr1235 (2), pTyr1356 (2), N-Term (1), Phosphospecific (1), Tyr1003 (1), Tyr1234, Tyr1235 (1), pSer222,pSer218 (1), pSer62,pThr58 (1), pTyr1249,pTyr1356 (1), pTyr1356,pTyr1349 (1)