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Details for Product No. ABIN966576

Chemokine (C-C Motif) Ligand 4 (CCL4) (C-Term), (AA 74-88) antibody

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Synonyms ACT2, AT744.1, G-26, HC21, LAG-1, LAG1, MIP-1-beta, MIP1B, MIP1B1, SCYA2, SCYA4, Scya4, Mip1-b, MIP-1BETA, MIP1b, SCY4A, Act-2, MIP-1B, Mip1b, CCL4, K203, CCL4L2
»Alternatives C-Term, AA 74-88
»Alternatives Mouse (Murine)
Clonality Polyclonal
»Alternatives Un-conjugated
»Alternatives Western Blotting (WB)
Pubmed 4 references available
Catalog no. ABIN966576
Quantity 100 µg
316.25 $   Plus shipping costs $45.00
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Availability Will be delivered in 5 to 7 Business Days
Immunogen A synthetic peptide corresponding to a sequence at the C-terminal of mouse MIP1b (74-88 aa), identical to the related mouse and rat sequence.
Alternative Name MIP-1b
Background Chemokine (C-C motif) ligand 4, also known as CCL4, is a protein which in humans is encoded by the CCL4 gene. It is a CC chemokine with specificity for CCR5 receptors. It is a chemoattractant for natural killer cells, monocytes and a variety of other immune cells. CCL4 is a major HIV-suppressive factor produced by CD8+ T cells. Performing-low memory CD8+ T cells that normally synthesize MIP-1-beta. Modi et al. (1991) assigned the SCYA4 gene to a slightly more distal location than had Irving et al. (1990): 17q21-q23 rather than 17q11-q21.
Restrictions For Research Use only
Reconstitution 0.2ml of distilled water will yield a concentration of 500µg/ml.
Buffer Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4
Preservative Thimerosal (Merthiolate), Sodium azide
Storage -20 °C
Product cited in: Irving, Zipfel, Balke et al.: "Two inflammatory mediator cytokine genes are closely linked and variably amplified on chromosome 17q." in: Nucleic acids research, Vol. 18, Issue 11, pp. 3261-70, 1990 (PubMed).

Cocchi, DeVico, Garzino-Demo et al.: "Identification of RANTES, MIP-1 alpha, and MIP-1 beta as the major HIV-suppressive factors produced by CD8+ T cells." in: Science (New York, N.Y.), Vol. 270, Issue 5243, pp. 1811-5, 1996 (PubMed).

Kamin-Lewis, Abdelwahab, Trang et al.: "Perforin-low memory CD8+ cells are the predominant T cells in normal humans that synthesize the beta -chemokine macrophage inflammatory protein-1beta." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 98, Issue 16, pp. 9283-8, 2001 (PubMed).

Bystry, Aluvihare, Welch et al.: "B cells and professional APCs recruit regulatory T cells via CCL4." in: Nature immunology, Vol. 2, Issue 12, pp. 1126-32, 2001 (PubMed).

Alternatives for antigen "Chemokine (C-C Motif) Ligand 4 (CCL4)", type "Antibodies"
Hosts (91), (8), (6), (3), (1)
Reactivities (67), (61), (37), (3), (1)
Applications (85), (65), (20), (16), (11), (11), (10), (5), (4), (1), (1), (1), (1), (1), (1), (1)
Conjugates (15), (4), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1)
Epitopes (5), (4), (3), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1)