MAP2K6 antibody (Mitogen-Activated Protein Kinase Kinase 6) (pSer207)

Details for Product anti-MAP2K6 Antibody No. ABIN966580, Supplier: Log in to see
Antigen
  • MAPKK6
  • MEK6
  • MKK6
  • PRKMK6
  • SAPKK-3
  • SAPKK3
  • Mkk6
  • Prkmk6
  • ANQ1
  • ARABIDOPSIS NQK1
  • ARABIDOPSIS THALIANA MAP KINASE KINASE 6
  • ATMKK6
  • MAP kinase kinase 6
  • MIK19.2
  • MIK19_2
  • MKK3
  • map2k3
  • zMKK3
  • mitogen-activated protein kinase kinase 6
  • MAP2K6
  • Map2k6
  • MKK6
  • map2k6
Alternatives
anti-Human MAP2K6 antibody for Western Blotting
Epitope
pSer207
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Reactivity
Human, Rat (Rattus)
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Host
Rabbit
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Conjugate
This MAP2K6 antibody is un-conjugated
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Application
Immunohistochemistry (IHC)
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Options
Supplier
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Immunogen The antiserum was produced against synthesized phosphopeptide derived from human MKK6 around the phosphorylation site of serine 207 (V-D-SP-V-A).
Specificity MKK6 (phospho-Ser207) antibody detects endogenous levels of MKK6 only when phosphorylated at serine207.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Alternative Name MKK6 (MAP2K6 Antibody Abstract)
Research Area Kinases/Phosphatases
Pathways MAPK Signaling, TLR Signaling, Activation of Innate immune Response, Regulation of Muscle Cell Differentiation, Toll-Like Receptors Cascades
Application Notes WB: 1:500~1:1000
IHC: 1:50~1:100.
Restrictions For Research Use only
Format Liquid
Concentration 100ug/100ul.
Buffer Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Product cited in: Wang, Chen, Liao, Deng, Zhou, Huang, Sun: "Sequential activation of the MEK-extracellular signal-regulated kinase and MKK3/6-p38 mitogen-activated protein kinase pathways mediates oncogenic ras-induced premature senescence." in: Molecular and cellular biology, Vol. 22, Issue 10, pp. 3389-403, 2002 (PubMed).

Background publications Raingeaud, Whitmarsh, Barrett, Dérijard, Davis: "MKK3- and MKK6-regulated gene expression is mediated by the p38 mitogen-activated protein kinase signal transduction pathway." in: Molecular and cellular biology, Vol. 16, Issue 3, pp. 1247-55, 1996 (PubMed).

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