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Matrix Metallopeptidase 10 (Stromelysin 2) (MMP10) (AA 410-422), (C-Term) antibody

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Antigen
  • AV377895
  • MMP-10
  • SL-2
  • STMY2
  • MMP-3
  • MMP10
Epitope
C-Term, AA 410-422
32
6
6
6
5
4
3
3
3
3
3
2
2
1
1
1
1
1
1
1
1
1
Reactivity
Human
137
16
14
Host
127
15
Clonality
Polyclonal
Conjugate
Un-conjugated
10
7
5
2
2
2
1
Application
Western Blotting (WB)
90
72
44
22
16
12
7
3
3
3
1
1
1
1
Supplier
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Immunogen A synthetic peptide corresponding to a sequence at the C-terminal of human MMP-10 (410-422 aa), identical to the related mouse and rat sequence.
Alternative Name MMP-10 (MMP10 Antibody Abstract)
Background Stromelysin-2 also known as matrix metalloproteinase-10 (MMP-10) or transin-2 is an enzyme that in humans is encoded by the MMP10 gene.Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The enzyme encoded by this gene degrades proteoglycans and fibronectin. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3.
Research Area Extracellular Matrix
Application Notes WB: The detection limit for MMP-10 is approximately 2.5ng/lane under non-reducing and reducing conditions.
Restrictions For Research Use only
Reconstitution 0.2ml of distilled water will yield a concentration of 500µg/ml.
Buffer Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4
Preservative Thimerosal (Merthiolate), Sodium azide
Storage -20 °C
Product cited in: Muller, Quantin, Gesnel et al.: "The collagenase gene family in humans consists of at least four members." in: The Biochemical journal, Vol. 253, Issue 1, pp. 187-92, 1988 (PubMed).

Jung, Warter, Rumpler: "Localization of stromelysin 2 gene to the q22.3-23 region of chromosome 11 by in situ hybridization." in: Annales de génétique, Vol. 33, Issue 1, pp. 21-3, 1990 (PubMed).