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Neurogenin 3 antibody (NEUROG3)

Details for Product anti-NEUROG3 Antibody No. ABIN966645, Supplier: Log in to see
Antigen
  • atoh4
  • Atoh5
  • atoh5
  • bHLHa7
  • bhlha7
  • Math4B
  • math4b
  • NEUROG3
  • neurog3
  • NGN-3
  • ngn-3
  • ngn2
  • Ngn3
  • ngn3
  • ngn3a
  • Relax
Reactivity
Human
100
39
17
2
1
1
1
1
Host
Mouse
84
29
2
Clonality (Clone)
Monoclonal ()
Conjugate
This Neurogenin 3 antibody is un-conjugated
6
6
5
4
4
4
1
1
1
1
1
1
1
1
1
Application
ELISA, Western Blotting (WB)
77
55
45
16
11
11
8
4
2
1
1
1
Supplier
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Immunogen Purified recombinant fragment of human Neurogenin-3 expressed in E. Coli.
Clone 6G2
Isotype IgG1
Purification Liquid
Alternative Name Neurogenin-3 (NEUROG3 Antibody Abstract)
Background Neurogenin-3 (NEUROG3), also known as NGN3, it is expressed in endocrine progenitor cells and is required for endocrine cell development in the pancreas and intestine. It belongs to a family of basic helix-loop-helix transcription factors involved in the determination of neural precursor cells in the neuroectoderm.
Synonyms: ngn3, Atoh5, Math4B, bHLHa7, NEUROG3
Molecular Weight 23kDa
Gene ID 50674
Application Notes Western Bloting: 1/500 - 1/2000.
ELISA: Propose dilution 1/10000.
Not yet tested in other applications.
Determining optimal working dilutions by titration test.
Restrictions For Research Use only
Format Liquid
Buffer PBS containing 50% glycerol
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C
Product cited in: Heremans, Van De Casteele, int Veld, Gradwohl, Serup, Madsen, Pipeleers, Heimberg: "Recapitulation of embryonic neuroendocrine differentiation in adult human pancreatic duct cells expressing neurogenin 3." in: The Journal of cell biology, Vol. 159, Issue 2, pp. 303-12, 2002 (PubMed).

Gradwohl, Dierich, LeMeur, Guillemot: "neurogenin3 is required for the development of the four endocrine cell lineages of the pancreas." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 97, Issue 4, pp. 1607-11, 2000 (PubMed).