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NFkB p100/p52 (pSer865) antibody

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(4), (3), (1), (1), (1), (1), (1), (1)
Human, Mouse (Murine), Rat (Rattus)
(16), (11), (10), (1)
Immunohistochemistry (IHC)
(13), (13), (7), (4), (3), (2), (1)
Pubmed 5 references available
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Quantity 100 μg
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Availability Will be delivered in 5 to 7 Business Days
Immunogen The antiserum was produced against synthesized phosphopeptide derived from human NF-B p100/p52 around the phosphorylation site of serine 865 (E-D-SP-A-Y).
Specificity NF-B p100/p52 (phospho-ser865) antibody detects endogenous levels of NF-B p100/p52 only when phosphorylated at serine 865.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using nonphosphopeptide corresponding to the phosphorylation site.
Alternative Name NF-kB p100/p52
Application Notes WB: 1:500~1:1000
IHC: 1:50~1:100.
Restrictions For Research Use only
Format Liquid
Concentration 100ug/100ul.
Buffer Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Product cited in: Tang, Li, Pan et al.: "[River continuum characteristics of Xiangxi River]." in: Ying yong sheng tai xue bao = The journal of applied ecology / Zhongguo sheng tai xue xue hui, Zhongguo ke xue yuan Shenyang ying yong sheng tai yan jiu suo zhu ban, Vol. 15, Issue 1, pp. 141-4, 2004 (PubMed).

Xiao, Harhaj, Sun: "NF-kappaB-inducing kinase regulates the processing of NF-kappaB2 p100." in: Molecular cell, Vol. 7, Issue 2, pp. 401-9, 2001 (PubMed).

Background publications Qu, Qing, Rabson et al.: "Tax deregulation of NF-kappaB2 p100 processing involves both beta-TrCP-dependent and -independent mechanisms." in: The Journal of biological chemistry, Vol. 279, Issue 43, pp. 44563-72, 2004 (PubMed).

Baeuerle, Baltimore: "NF-kappa B: ten years after." in: Cell, Vol. 87, Issue 1, pp. 13-20, 1996 (PubMed).

Baeuerle, Henkel: "Function and activation of NF-kappa B in the immune system." in: Annual review of immunology, Vol. 12, pp. 141-79, 1994 (PubMed).

Catalog No. ABIN966651
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