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Details for Product No. ABIN966660

Nuclear Factor-KB P65 (NFkBP65) (pSer536) antibody

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Antigen
Synonyms C-Rel, Xrel2, c-rel, rel-A, v-rel, xrel, zgc:100833, p65, NFkB
Epitope
»Alternatives pSer536
Reactivity
»Alternatives Human, Mouse (Murine), Rat (Rattus)
Host
»Alternatives Rabbit
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives Immunohistochemistry (IHC)
Pubmed 6 references available
Catalog no. ABIN966660
Quantity 100 µg
Price
385.00 $   Plus shipping costs $45.00
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Availability Will be delivered in 5 to 7 Business Days
Immunogen The antiserum was produced against synthesized phosphopeptide derived from human NF-B p65 around the phosphorylation site of serine 536 (F-S-SP-I-A).
Specificity NF-B p65 (phospho-Ser536) antibody detects endogenous levels of NF-B p65 only when phosphorylated at serine 536.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using nonphosphopeptide corresponding to the phosphorylation site.
Alternative Name NF-kB p65
Application Notes WB: 1:500~1:1000
IHC: 1:50~1:100.
Restrictions For Research Use only
Format Liquid
Concentration 100ug/100ul.
Buffer Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol
Preservative Sodium azide
Storage -20 °C
Product cited in: Baeuerle, Henkel: "Function and activation of NF-kappa B in the immune system." in: Annual review of immunology, Vol. 12, pp. 141-79, 1994 (PubMed).

Baeuerle, Baltimore: "NF-kappa B: ten years after." in: Cell, Vol. 87, Issue 1, pp. 13-20, 1996 (PubMed).

Anwar, Fazal, Malik et al.: "RhoA/Rho-associated kinase pathway selectively regulates thrombin-induced intercellular adhesion molecule-1 expression in endothelial cells via activation of I kappa B kinase beta and phosphorylation of RelA/p65." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 173, Issue 11, pp. 6965-72, 2004 (PubMed).

Doyle, Jefferies, ONeill: "Bruton's tyrosine kinase is involved in p65-mediated transactivation and phosphorylation of p65 on serine 536 during NFkappaB activation by lipopolysaccharide." in: The Journal of biological chemistry, Vol. 280, Issue 25, pp. 23496-501, 2005 (PubMed).

Doyle, Monga, Montgomery et al.: "Arrhythmogenic right ventricular cardiomyopathy with implantable cardioverter defibrillator placement in pregnancy." in: The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians, Vol. 18, Issue 2, pp. 141-4, 2005 (PubMed).

Gires, Klein, Baeuerle: "On the abundance of EpCAM on cancer stem cells." in: Nature reviews. Cancer, Vol. 9, Issue 2, pp. 143; author reply 143, 2009 (PubMed).

Alternatives for antigen "Nuclear Factor-KB P65 (NFkBP65)", type "Antibodies"
Hosts (691), (54), (6), (4), (1)
Reactivities (734), (425), (347), (81), (78), (78), (38), (8), (6), (3), (2), (2), (2), (2), (2), (1)
Applications (554), (267), (247), (189), (111), (104), (100), (31), (17), (14), (13), (7), (5), (4), (3), (2), (2), (1)
Conjugates (16), (11), (10), (10), (10), (10), (10), (10), (10), (10), (10), (2), (1), (1)
Epitopes (46), (43), (43), (42), (31), (31), (29), (28), (27), (22), (18), (15), (12), (7), (6), (6), (6), (4), (4), (4), (4), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
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