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CDKN1B antibody (Cyclin-Dependent Kinase Inhibitor 1B (p27, Kip1))

Details for Product anti-CDKN1B Antibody No. ABIN966734, Supplier: Log in to see
Antigen
  • CDKN1B
  • CIB
  • CIBP
  • KIP1
  • PRKDCIP
  • SIP2-28
  • p27Kip1
  • AA408329
  • AI843786
  • Kip1
  • p27
  • CDKN4
  • Cdki1b
  • P27KIP1
  • MEN1B
  • MEN4
  • cdkn1bl
  • cdkn1b
  • sb:cb611
  • wu:fb63g10
  • wu:fb64g10
  • wu:fe18e03
  • FAM14D
  • ISG12
  • ISG12A
  • P27
  • 1500011J20Rik
  • 2610202L11Rik
  • Bridge-1
Alternatives
anti-Human CDKN1B antibody for Immunohistochemistry (Frozen Sections)
Reactivity
Human, Mouse (Murine), Rat (Rattus)
579
201
147
22
21
17
9
8
6
6
3
2
2
2
2
1
1
Host
Rabbit
496
95
35
2
2
1
Clonality
Polyclonal
Conjugate
This CDKN1B antibody is un-conjugated
31
29
27
25
25
25
6
2
2
2
2
2
2
2
2
Application
Immunohistochemistry (IHC)
424
303
177
103
85
74
45
30
24
16
12
6
3
1
1
1
Supplier
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Immunogen The antiserum was produced against synthesized non-phosphopeptide derived from human p27Kip1 around the phosphorylation site of serine 10 (N-G-SP-P-S).
Specificity P27Kip1 (Ab-10) antibody detects endogenous levels of total p27Kip1 protein.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Alternative Name p27Kip1 (CDKN1B Antibody Abstract)
Pathways Cell Division Cycle, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
Application Notes WB: 1:500~1:1000
IHC: 1:50~1:100.
Restrictions For Research Use only
Format Liquid
Concentration 100ug/100ul.
Buffer Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Product cited in: Le, Claret, Lammayot et al.: "The role of cyclin-dependent kinase inhibitor p27Kip1 in anti-HER2 antibody-induced G1 cell cycle arrest and tumor growth inhibition." in: The Journal of biological chemistry, Vol. 278, Issue 26, pp. 23441-50, 2003 (PubMed).

Connor, Kotchetkov, Cariou et al.: "CRM1/Ran-mediated nuclear export of p27(Kip1) involves a nuclear export signal and links p27 export and proteolysis." in: Molecular biology of the cell, Vol. 14, Issue 1, pp. 201-13, 2003 (PubMed).

Chopra, Fernandez De Mattos, Lam et al.: "Jab1 co-activation of c-Jun is abrogated by the serine 10-phosphorylated form of p27Kip1." in: The Journal of biological chemistry, Vol. 277, Issue 36, pp. 32413-6, 2002 (PubMed).

Boehm, Yoshimoto, Crook et al.: "A growth factor-dependent nuclear kinase phosphorylates p27(Kip1) and regulates cell cycle progression." in: The EMBO journal, Vol. 21, Issue 13, pp. 3390-401, 2002 (PubMed).

Background publications McAllister, Becker-Hapak, Pintucci et al.: "Novel p27(kip1) C-terminal scatter domain mediates Rac-dependent cell migration independent of cell cycle arrest functions." in: Molecular and cellular biology, Vol. 23, Issue 1, pp. 216-28, 2002 (PubMed).