anti-p53 antibody (Tumor Protein P53) (pSer15)

Details for Product anti-TP53 Antibody No. ABIN966755
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Antigen
Synonyms tp53, p53, TP53, Tp53, bbl, bfy, bhy, p44, TpMs, BCC7, LFS1, P53, TRP53, Trp53, Xp53, brp53, drp53, etID22686.5, fb40d06, wu:fb40d06, zgc:111919
Epitope
pSer15
(65), (54), (54), (47), (46), (45), (45), (42), (40), (39), (36), (34), (34), (27), (25), (22), (19), (19), (15), (12), (12), (12), (12), (12), (10), (10), (9), (9), (8), (8), (8), (7), (7), (7), (7), (7), (7), (7), (7), (6), (6), (6), (6), (6), (6), (6), (6), (6), (6), (6), (6), (6), (5), (5), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Human
(1688), (324), (264), (48), (16), (11), (8), (6), (6), (5), (5), (5), (5), (4), (4), (3), (3), (2), (2), (2), (2), (1)
Host
Rabbit
(1223), (560), (8), (5), (3), (1)
Conjugate
This p53 antibody is un-conjugated
(52), (45), (33), (29), (24), (24), (17), (16), (16), (16), (16), (16), (16), (16), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1)
Application
Immunohistochemistry (IHC)
(1394), (590), (516), (370), (344), (321), (209), (162), (110), (79), (37), (31), (30), (29), (19), (16), (14), (6), (5), (4), (3), (3), (2), (2), (2), (1), (1), (1), (1)
Pubmed 3 references available
Quantity 100 μg
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Immunogen The antiserum was produced against synthesized phosphopeptide derived from human p53 around the phosphorylation site of serine 15 (P-L-SP-Q-E).
Specificity P53 (phospho-Ser15) antibody detects endogenous levels of p53 only when phosphorylated at serine15.
Alternative Name p53 (TP53 Antibody Abstract)
Research Area Cancer, Cell Cycle, Transcription Factors, DNA/RNA, Apoptosis/Necrosis
Restrictions For Research Use only
Format Liquid
Concentration 100ug/100ul.
Buffer Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Product cited in: Hirao, Kong, Matsuoka et al.: "DNA damage-induced activation of p53 by the checkpoint kinase Chk2." in: Science (New York, N.Y.), Vol. 287, Issue 5459, pp. 1824-7, 2000 (PubMed).

Shieh, Taya, Prives: "DNA damage-inducible phosphorylation of p53 at N-terminal sites including a novel site, Ser20, requires tetramerization." in: The EMBO journal, Vol. 18, Issue 7, pp. 1815-23, 1999 (PubMed).

Honda, Tanaka, Yasuda: "Oncoprotein MDM2 is a ubiquitin ligase E3 for tumor suppressor p53." in: FEBS letters, Vol. 420, Issue 1, pp. 25-7, 1998 (PubMed).

Validation Images
Catalog No. ABIN966755
398.75 $
Plus shipping costs $45.00
Quantity
Price
100 μg
398.75 $

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