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Tumor Protein P53 (TP53) (pSer15) antibody

Antigen

Tumor Protein P53 (TP53)
Synonyms p53, LFS1, TRP53, FLJ92943, P53, Trp53, MGC112612, brp53, drp53, fb40d06, wu:fb40d06, zgc:111919, TP53, bbl, bfy, bhy, p44, Tp53, tp53
Binding Site
Alternatives

pSer15
Host
Alternatives

Rabbit
Reactivity
Alternatives

Human
Conjugate
Alternatives Un-conjugated
Application
Alternatives Immunohistochemistry (IHC)
3 references available
Catalog no. ABIN966755
Quantity 100ug  (100ug/100ul.)  (Variants)
Price 385.00 $   Plus shipping costs $45.00
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Additional Information
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Alternative name p53
Immunogen The antiserum was produced against synthesized phosphopeptide derived from human p53 around the phosphorylation site of serine 15 (P-L-SP-Q-E).
Specificity P53 (phospho-Ser15) antibody detects endogenous levels of p53 only when phosphorylated at serine15.

Application Details
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Concentration 100ug/100ul.
Buffer Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol
Preservative 0.02% Sodium Azide
Storage Store at -20°C/1 year.
Research Area Cancer, Cell Cycle, Transcription Factors, DNA/RNA, Apoptosis/Necrosis
Restrictions For Research Use only

Publications
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Product Honda, Tanaka, Yasuda: "Oncoprotein MDM2 is a ubiquitin ligase E3 for tumor suppressor p53." in: FEBS letters, Vol. 420, Issue 1, pp. 25-7, 1998 (PubMed).

Shieh, Taya, Prives: "DNA damage-inducible phosphorylation of p53 at N-terminal sites including a novel site, Ser20, requires tetramerization." in: The EMBO journal, Vol. 18, Issue 7, pp. 1815-23, 1999 (PubMed).

Hirao, Kong, Matsuoka et al.: "DNA damage-induced activation of p53 by the checkpoint kinase Chk2." in: Science (New York, N.Y.), Vol. 287, Issue 5459, pp. 1824-7, 2000 (PubMed).

Alternatives
Application Details Publications Variants back to top

Alternatives for antigen "Tumor Protein P53 (TP53)", type "Antibodies"
Hosts Rabbit (676), Mouse (309), Sheep (4), Escherichia Coli (E. coli) (1), Rat (1), Recombinant (1)
Reactivities Human (933), Mouse (Murine) (251), Rat (Rattus) (206), Cow (Bovine) (121), Dog (Canine) (113), Horse (Equine) (113), Pig (Porcine) (95), Sheep (Ovine) (93), Monkey (42), Guinea Pig (36), Chicken (20), Primate (7), Hamster (6), Rabbit (6), Cat (Feline) (5), Xenopus laevis (3), Mammalian (2), Bird (Avian) (1)
Applications Western Blotting (WB) (609), Immunofluorescence (IF) (355), ELISA (284), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (262), Immunoprecipitation (IP) (177), Immunohistochemistry (IHC) (157), Flow Cytometry (FACS) (105), Immunocytochemistry (ICC) (60), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (52), Immunohistochemistry (Frozen Sections) (IHC (fro)) (51), Immunohistochemistry (Fixed) (IHC (fx)) (22), Immunoelectron Microscopy (IEM) (16), Dot Blot (Dot) (9), Chromatin Immunoprecipitation (ChiP) (8), Gel Shift (GS) (5), Radioimmunoassay (RIA) (4), Chromatin Immunoprecipitation (ChIP) (2), Affinity Purification (AP) (1), Cellular Assay (CA) (1), Dot Blot (DB) (1), ELISA (Capture) (1), ELISA (Detection) (1), Immunoassay (IA) (1), Immunostaining (ISt) (1), Transfected cell culture (TCC) (1)
Conjugates FITC (32), Biotin (27), HRP (18), PE (17), Alexa Fluor 350 (16), Alexa Fluor 488 (16), Alexa Fluor 555 (16), Alexa Fluor 647 (16), Cy3 (16), Cy5 (16), Cy5.5 (16), Cy7 (16), Gold (16), PE,Cy3 (14), PE,Cy5 (14), PE,Cy5.5 (14), PE,Cy7 (14), RPE (3), PE-Cy3 (2), PE-Cy5 (2), PE-Cy5.5 (2), PE-Cy7 (2)
Epitopes pSer315 (34), pSer37 (33), pSer46 (33), pSer15 (31), pSer392 (31), pThr18 (31), pSer33 (30), pSer6 (30), pSer20 (29), C-Term (28), AA 20-25 (27), pSer9 (26), N-Term (22), pSer376 (22), pThr55 (21), acLys382 (20), pThr81 (19), AA 371-380 (7), AA 10-16 (5), AA 16-25 (5), AA 26-35 (5), Ser37 (5), Ser46 (5), AA 14-389 (4), AA 56-65 (4), Ser315 (4), AA 181-190 (3), AA 213-217 (3), AA 32-79 (3), AA 35-45 (3), AA 46-53 (3), AA 46-55 (3), AA 88-109 (3), pSer378 (3), AA 16-30 (2), AA 306-393 (2), AA 378-393 (2), Ser15 (2), Ser33 (2), Ser6 (2), Thr18 (2), Thr55 (2), acLys317 (2), acLys379 (2), acLys386 (2), AA 1-12 (1), AA 14-289 (1), AA 15-40 (1), AA 156-214 (1), AA 20-31 (1), AA 361-382 (1), AA 367-381 (1), AA 37-45 (1), AA 37-5 (1), AA 383-393 (1), Internal Region (1), Mutant (1), Mutant,AA 213-217 (1), Ser15,Phosphospecific (1), Ser20 (1), Ser392 (1), Wild type,Mutant (1), Wild type,Mutant,AA 32-79 (1), Wild type,Mutant,AA 370-378 (1), Wildtype (1), acLys373 (1), pSer332 (1), pSer366 (1), pSer392,AA 378-393 (1), pSer63 (1), pSer95 (1), pThr387 (1), phospho (1)