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Tumor Protein P53 (TP53) (pSer315) antibody

Antigen

Tumor Protein P53 (TP53)
Synonyms p53, LFS1, TRP53, FLJ92943, P53, Trp53, MGC112612, brp53, drp53, fb40d06, wu:fb40d06, zgc:111919, TP53, bbl, bfy, bhy, p44, Tp53, tp53
Binding Site
Alternatives

pSer315
Host
Alternatives

Rabbit
Reactivity
Alternatives

Human
Conjugate
Alternatives Un-conjugated
Application
Alternatives Immunohistochemistry (IHC)
4 references available
Catalog no. ABIN966756
Quantity 100ug  (100ug/100ul.)  (Variants)
Price 385.00 $   Plus shipping costs $45.00
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Alternative name p53
Immunogen The antiserum was produced against synthesized phosphopeptide derived from human p53 around the phosphorylation site of serine 315 (S-S-SP-P-Q).
Specificity P53 (phospho-Ser315) antibody detects endogenous levels of p53 only when phosphorylated at serine 315.

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Concentration 100ug/100ul.
Buffer Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol
Preservative 0.02% Sodium Azide
Storage Store at -20°C/1 year.
Research Area Cancer, Cell Cycle, Transcription Factors, DNA/RNA, Apoptosis/Necrosis
Restrictions For Research Use only

Publications
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Product Ullrich, Sakaguchi, Lees-Miller et al.: "Phosphorylation at Ser-15 and Ser-392 in mutant p53 molecules from human tumors is altered compared to wild-type p53." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 90, Issue 13, pp. 5954-8, 1993 (PubMed).

Lohrum, Scheidtmann: "Differential effects of phosphorylation of rat p53 on transactivation of promoters derived from different p53 responsive genes." in: Oncogene, Vol. 13, Issue 12, pp. 2527-39, 1997 (PubMed).

Lu, Fisher, Bailey et al.: "The CDK7-cycH-p36 complex of transcription factor IIH phosphorylates p53, enhancing its sequence-specific DNA binding activity in vitro." in: Molecular and cellular biology, Vol. 17, Issue 10, pp. 5923-34, 1997 (PubMed).

Merrick, Zhou, Martin et al.: "Site-specific phosphorylation of human p53 protein determined by mass spectrometry." in: Biochemistry, Vol. 40, Issue 13, pp. 4053-66, 2001 (PubMed).

Alternatives
Application Details Publications Variants back to top

Alternatives for antigen "Tumor Protein P53 (TP53)", type "Antibodies"
Hosts Rabbit (473), Mouse (290), Sheep (4), Escherichia Coli (E. coli) (1), Rat (1), Recombinant (1)
Reactivities Human (705), Mouse (Murine) (176), Rat (Rattus) (146), Cow (Bovine) (69), Dog (Canine) (49), Horse (Equine) (48), Pig (Porcine) (43), Sheep (Ovine) (41), Monkey (40), Guinea Pig (10), Primate (8), Chicken (7), Rabbit (7), Cat (Feline) (5), Hamster (5), Mammalian (2), Xenopus laevis (2), Bird (Avian) (1)
Applications Western Blotting (WB) (543), ELISA (232), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (215), Immunofluorescence (IF) (199), Immunoprecipitation (IP) (162), Immunohistochemistry (IHC) (146), Flow Cytometry (FACS) (93), Immunocytochemistry (ICC) (59), Immunohistochemistry (Frozen Sections) (IHC (fro)) (50), Immunohistochemistry (Fixed) (IHC (fx)) (22), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (10), Dot Blot (Dot) (9), Chromatin Immunoprecipitation (ChiP) (8), Gel Shift (GS) (5), Radioimmunoassay (RIA) (4), Immunoelectron Microscopy (IEM) (2), Affinity Purification (AP) (1), Cellular Assay (CA) (1), Dot Blot (DB) (1), ELISA (Capture) (1), ELISA (Detection) (1), Immunoassay (IA) (1), Immunostaining (ISt) (1), Transfected cell culture (TCC) (1)
Conjugates FITC (17), Alexa Fluor 350 (15), Alexa Fluor 488 (15), Alexa Fluor 555 (15), Alexa Fluor 647 (15), Biotin (13), PE,Cy5.5 (13), HRP (4), PE (3), RPE (3), Cy3 (2), Cy5 (2), Cy5.5 (2), Cy7 (2), Gold (2), PE-Cy3 (2), PE-Cy5 (2), PE-Cy5.5 (2), PE-Cy7 (2), Un-conjugated (2)
Epitopes AA 20-25 (20), N-Term (18), pSer37 (17), pSer46 (16), C-Term (15), pSer15 (15), pSer315 (14), pSer33 (14), pThr18 (14), AA 1-393 (13), pSer20 (13), pSer6 (13), pSer392 (12), pSer9 (11), pSer376 (7), pThr55 (7), Ser37 (5), Ser46 (5), pThr81 (5), AA 14-389 (4), AA 371-380 (4), Ser315 (4), AA 10-16 (3), AA 26-35 (3), AA 32-79 (3), AA 35-45 (3), AA 56-65 (3), pSer378 (3), AA 16-25 (2), AA 16-30 (2), AA 181-190 (2), AA 213-217 (2), AA 306-393 (2), AA 378-393 (2), AA 46-53 (2), AA 46-55 (2), AA 88-109 (2), Ser15 (2), Ser33 (2), Ser6 (2), Thr18 (2), Thr55 (2), acLys317 (2), acLys379 (2), acLys382 (2), acLys386 (2), AA 1-12 (1), AA 14-289 (1), AA 15-40 (1), AA 156-214 (1), AA 361-382 (1), AA 367-381 (1), AA 37-45 (1), AA 37-5 (1), AA 383-393 (1), Internal Region (1), Mutant (1), Mutant,AA 213-217 (1), Ser15,Phosphospecific (1), Ser20 (1), Ser392 (1), Wild type,Mutant (1), Wild type,Mutant,AA 32-79 (1), Wild type,Mutant,AA 370-378 (1), Wildtype (1), acLys373 (1), pSer299 (1), pSer332 (1), pSer366 (1), pSer371 (1), pSer392,AA 378-393 (1), pSer63 (1), pSer95 (1), pThr387 (1), pTyr757 (1), phospho (1)