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Details for Product No. ABIN966756

Tumor Protein P53 (TP53) (pSer315) antibody

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Antigen
Synonyms BCC7, LFS1, P53, TRP53, p53, Trp53, bbl, bfy, bhy, p44, Tp53, Xp53, brp53, drp53, etID22686.5, fb40d06, wu:fb40d06, zgc:111919, tp53
Epitope
»Alternatives pSer315
Reactivity
»Alternatives Human
Host
»Alternatives Rabbit
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives Immunohistochemistry (IHC)
Pubmed 4 references available
Catalog no. ABIN966756
Quantity 100 µg
Price
385.00 $   Plus shipping costs $45.00
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Availability Will be delivered in 5 to 7 Business Days
Immunogen The antiserum was produced against synthesized phosphopeptide derived from human p53 around the phosphorylation site of serine 315 (S-S-SP-P-Q).
Specificity P53 (phospho-Ser315) antibody detects endogenous levels of p53 only when phosphorylated at serine 315.
Alternative Name p53
Research Area Cancer, Cell Cycle, Transcription Factors, DNA/RNA, Apoptosis/Necrosis
Restrictions For Research Use only
Format Liquid
Concentration 100ug/100ul.
Buffer Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol
Preservative Sodium azide
Storage -20 °C
Product cited in: Ullrich, Sakaguchi, Lees-Miller et al.: "Phosphorylation at Ser-15 and Ser-392 in mutant p53 molecules from human tumors is altered compared to wild-type p53." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 90, Issue 13, pp. 5954-8, 1993 (PubMed).

Lohrum, Scheidtmann: "Differential effects of phosphorylation of rat p53 on transactivation of promoters derived from different p53 responsive genes." in: Oncogene, Vol. 13, Issue 12, pp. 2527-39, 1997 (PubMed).

Lu, Fisher, Bailey et al.: "The CDK7-cycH-p36 complex of transcription factor IIH phosphorylates p53, enhancing its sequence-specific DNA binding activity in vitro." in: Molecular and cellular biology, Vol. 17, Issue 10, pp. 5923-34, 1997 (PubMed).

Merrick, Zhou, Martin et al.: "Site-specific phosphorylation of human p53 protein determined by mass spectrometry." in: Biochemistry, Vol. 40, Issue 13, pp. 4053-66, 2001 (PubMed).

Alternatives for antigen "Tumor Protein P53 (TP53)", type "Antibodies"
Hosts (859), (442), (5), (3), (2), (2), (1)
Reactivities (1223), (289), (239), (86), (80), (67), (32), (25), (16), (11), (8), (8), (8), (7), (4), (3), (3), (3), (2), (2), (2), (2), (2), (2), (1), (1)
Applications (948), (438), (376), (264), (263), (193), (160), (143), (90), (77), (22), (16), (9), (7), (6), (6), (5), (3), (3), (2), (2), (2), (2), (1), (1), (1), (1)
Conjugates (37), (29), (19), (16), (16), (16), (16), (16), (16), (16), (16), (4), (3), (3), (2), (1), (1)
Epitopes (49), (42), (40), (38), (38), (37), (35), (35), (33), (33), (30), (30), (26), (21), (17), (17), (15), (9), (8), (7), (6), (6), (6), (6), (5), (5), (5), (5), (5), (5), (5), (5), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (3), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
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