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Tumor Protein P53 (TP53) (pSer46) antibody

Antigen

Tumor Protein P53 (TP53)
Synonyms p53, LFS1, TRP53, FLJ92943, P53, Trp53, MGC112612, brp53, drp53, fb40d06, wu:fb40d06, zgc:111919, TP53, bbl, bfy, bhy, p44, Tp53, tp53
Binding Site
Alternatives

pSer46
Host
Alternatives

Rabbit
Reactivity
Alternatives

Human
Conjugate
Alternatives Un-conjugated
Application
Alternatives Immunohistochemistry (IHC)
4 references available
Catalog no. ABIN966757
Quantity 100ug  (100ug/100ul.)  (Variants)
Price 385.00 $   Plus shipping costs $45.00
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Additional Information
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Alternative name p53
Immunogen The antiserum was produced against synthesized phosphopeptide derived from human p53 around the phosphorylation site of serine 46 (M-L-SP-P-D).
Specificity P53 (phospho-Ser46) antibody detects endogenous levels of p53 only when phosphorylated at serine 46.

Application Details
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Concentration 100ug/100ul.
Buffer Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol
Preservative 0.02% Sodium Azide
Storage Store at -20°C/1 year.
Research Area Cancer, Cell Cycle, Transcription Factors, DNA/RNA, Apoptosis/Necrosis
Restrictions For Research Use only

Publications
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Product Patrick, Zhou, Kwon et al.: "p35, the neuronal-specific activator of cyclin-dependent kinase 5 (Cdk5) is degraded by the ubiquitin-proteasome pathway." in: The Journal of biological chemistry, Vol. 273, Issue 37, pp. 24057-64, 1998 (PubMed).

Dhavan, Tsai: "A decade of CDK5." in: Nature reviews. Molecular cell biology, Vol. 2, Issue 10, pp. 749-59, 2001 (PubMed).

Mayo, Seo, Jackson et al.: "Phosphorylation of human p53 at serine 46 determines promoter selection and whether apoptosis is attenuated or amplified." in: The Journal of biological chemistry, Vol. 280, Issue 28, pp. 25953-9, 2005 (PubMed).

Di Stefano, Soddu, Sacchi et al.: "HIPK2 contributes to PCAF-mediated p53 acetylation and selective transactivation of p21Waf1 after nonapoptotic DNA damage." in: Oncogene, Vol. 24, Issue 35, pp. 5431-42, 2005 (PubMed).

Alternatives
Application Details Publications Variants back to top

Alternatives for antigen "Tumor Protein P53 (TP53)", type "Antibodies"
Hosts Rabbit (485), Mouse (290), Sheep (4), Escherichia Coli (E. coli) (1), Rat (1), Recombinant (1)
Reactivities Human (717), Mouse (Murine) (182), Rat (Rattus) (152), Cow (Bovine) (69), Dog (Canine) (49), Horse (Equine) (48), Pig (Porcine) (43), Sheep (Ovine) (41), Monkey (40), Guinea Pig (10), Primate (8), Chicken (7), Rabbit (7), Cat (Feline) (5), Hamster (5), Mammalian (2), Xenopus laevis (2), Bird (Avian) (1)
Applications Western Blotting (WB) (552), ELISA (244), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (215), Immunofluorescence (IF) (199), Immunoprecipitation (IP) (162), Immunohistochemistry (IHC) (149), Flow Cytometry (FACS) (93), Immunocytochemistry (ICC) (59), Immunohistochemistry (Frozen Sections) (IHC (fro)) (50), Immunohistochemistry (Fixed) (IHC (fx)) (22), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (10), Dot Blot (Dot) (9), Chromatin Immunoprecipitation (ChiP) (8), Gel Shift (GS) (5), Radioimmunoassay (RIA) (4), Immunoelectron Microscopy (IEM) (2), Affinity Purification (AP) (1), Cellular Assay (CA) (1), Dot Blot (DB) (1), ELISA (Capture) (1), ELISA (Detection) (1), Immunoassay (IA) (1), Immunostaining (ISt) (1), Transfected cell culture (TCC) (1)
Conjugates FITC (17), Alexa Fluor 350 (15), Alexa Fluor 488 (15), Alexa Fluor 555 (15), Alexa Fluor 647 (15), Biotin (13), PE,Cy5.5 (13), HRP (4), PE (3), RPE (3), Cy3 (2), Cy5 (2), Cy5.5 (2), Cy7 (2), Gold (2), PE-Cy3 (2), PE-Cy5 (2), PE-Cy5.5 (2), PE-Cy7 (2), Un-conjugated (2)
Epitopes C-Term (27), AA 20-25 (20), N-Term (18), pSer37 (17), pSer15 (15), pSer315 (15), pSer46 (15), pSer33 (14), pThr18 (14), AA 1-393 (13), pSer20 (13), pSer6 (13), pSer392 (12), pSer9 (11), pSer376 (7), pThr55 (7), Ser37 (5), Ser46 (5), pThr81 (5), AA 14-389 (4), AA 371-380 (4), Ser315 (4), AA 10-16 (3), AA 26-35 (3), AA 32-79 (3), AA 35-45 (3), AA 56-65 (3), pSer378 (3), AA 16-25 (2), AA 16-30 (2), AA 181-190 (2), AA 213-217 (2), AA 306-393 (2), AA 378-393 (2), AA 46-53 (2), AA 46-55 (2), AA 88-109 (2), Ser15 (2), Ser33 (2), Ser6 (2), Thr18 (2), Thr55 (2), acLys317 (2), acLys379 (2), acLys382 (2), acLys386 (2), AA 1-12 (1), AA 14-289 (1), AA 15-40 (1), AA 156-214 (1), AA 361-382 (1), AA 367-381 (1), AA 37-45 (1), AA 37-5 (1), AA 383-393 (1), Internal Region (1), Mutant (1), Mutant,AA 213-217 (1), Ser15,Phosphospecific (1), Ser20 (1), Ser392 (1), Wild type,Mutant (1), Wild type,Mutant,AA 32-79 (1), Wild type,Mutant,AA 370-378 (1), Wildtype (1), acLys373 (1), pSer299 (1), pSer332 (1), pSer366 (1), pSer371 (1), pSer392,AA 378-393 (1), pSer63 (1), pSer95 (1), pThr387 (1), pTyr757 (1), phospho (1)