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Details for Product No. ABIN966757

Tumor Protein P53 (TP53) (pSer46) antibody

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Antigen
Synonyms BCC7, LFS1, P53, TRP53, p53, Trp53, bbl, bfy, bhy, p44, Tp53, Xp53, brp53, drp53, etID22686.5, fb40d06, wu:fb40d06, zgc:111919, tp53
Epitope
»Alternatives pSer46
Reactivity
»Alternatives Human
Host
»Alternatives Rabbit
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives Immunohistochemistry (IHC)
Pubmed 4 references available
Catalog no. ABIN966757
Quantity 100 µg
Price
385.00 $   Plus shipping costs $45.00
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Availability Will be delivered in 5 to 7 Business Days
Immunogen The antiserum was produced against synthesized phosphopeptide derived from human p53 around the phosphorylation site of serine 46 (M-L-SP-P-D).
Specificity P53 (phospho-Ser46) antibody detects endogenous levels of p53 only when phosphorylated at serine 46.
Alternative Name p53
Research Area Cancer, Cell Cycle, Transcription Factors, DNA/RNA, Apoptosis/Necrosis
Restrictions For Research Use only
Format Liquid
Concentration 100ug/100ul.
Buffer Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol
Preservative Sodium azide
Storage -20 °C
Product cited in: Patrick, Zhou, Kwon et al.: "p35, the neuronal-specific activator of cyclin-dependent kinase 5 (Cdk5) is degraded by the ubiquitin-proteasome pathway." in: The Journal of biological chemistry, Vol. 273, Issue 37, pp. 24057-64, 1998 (PubMed).

Dhavan, Tsai: "A decade of CDK5." in: Nature reviews. Molecular cell biology, Vol. 2, Issue 10, pp. 749-59, 2001 (PubMed).

Mayo, Seo, Jackson et al.: "Phosphorylation of human p53 at serine 46 determines promoter selection and whether apoptosis is attenuated or amplified." in: The Journal of biological chemistry, Vol. 280, Issue 28, pp. 25953-9, 2005 (PubMed).

Di Stefano, Soddu, Sacchi et al.: "HIPK2 contributes to PCAF-mediated p53 acetylation and selective transactivation of p21Waf1 after nonapoptotic DNA damage." in: Oncogene, Vol. 24, Issue 35, pp. 5431-42, 2005 (PubMed).

Alternatives for antigen "Tumor Protein P53 (TP53)", type "Antibodies"
Hosts (859), (430), (5), (3), (2), (2), (1)
Reactivities (1211), (289), (227), (86), (80), (67), (32), (25), (16), (11), (8), (8), (8), (7), (4), (3), (3), (3), (2), (2), (2), (2), (2), (2), (1), (1)
Applications (945), (435), (373), (264), (263), (193), (150), (143), (90), (77), (22), (16), (9), (7), (6), (6), (5), (3), (3), (2), (2), (2), (2), (1), (1), (1), (1)
Conjugates (36), (28), (18), (15), (15), (15), (15), (15), (15), (15), (15), (4), (3), (3), (2), (1), (1)
Epitopes (49), (42), (40), (39), (38), (36), (35), (35), (33), (33), (30), (30), (26), (21), (17), (17), (15), (9), (8), (7), (6), (6), (6), (6), (5), (5), (5), (5), (5), (5), (5), (5), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (3), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
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