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Details for Product No. ABIN966765

Docking Protein 1, 62kDa (Downstream of tyrosine Kinase 1) (DOK1) (pTyr398) antibody

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Antigen
Synonyms 4432404K01Rik, ARTC4, DO, DOK1, P62DOK, AW557123, p62DOK
Epitope
»Alternatives pTyr398
Reactivity
»Alternatives Human, Mouse (Murine), Rat (Rattus)
Host
»Alternatives Rabbit
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives Immunohistochemistry (IHC)
Pubmed 3 references available
Catalog no. ABIN966765
Quantity 100 µg
Price
385.00 $   Plus shipping costs $45.00
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Availability Will be delivered in 5 to 7 Business Days
Immunogen The antiserum was produced against synthesized phosphopeptide derived from human p62Dok around the phosphorylation site of tyrosine 398 (E-G-YP-E-L).
Specificity P62Dok (phospho-Tyr398) antibody detects endogenous levels of p62Dok only when phosphorylated at tyrosine 398.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using nonphosphopeptide corresponding to the phosphorylation site.
Alternative Name p62Dok
Application Notes WB: 1:500~1:1000.
Restrictions For Research Use only
Format Liquid
Concentration 100ug/100ul.
Buffer Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol
Preservative Sodium azide
Storage -20 °C
Product cited in: Wick, Dong, Hu et al.: "Insulin receptor-mediated p62dok tyrosine phosphorylation at residues 362 and 398 plays distinct roles for binding GTPase-activating protein and Nck and is essential for inhibiting insulin-stimulated activation of Ras and Akt." in: The Journal of biological chemistry, Vol. 276, Issue 46, pp. 42843-50, 2001 (PubMed).

Yopp, Ochando, Mao et al.: "Sphingosine 1-phosphate receptors regulate chemokine-driven transendothelial migration of lymph node but not splenic T cells." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 175, Issue 5, pp. 2913-24, 2005 (PubMed).

Simoncic, Bourdeau, Lee-Loy et al.: "T-cell protein tyrosine phosphatase (Tcptp) is a negative regulator of colony-stimulating factor 1 signaling and macrophage differentiation." in: Molecular and cellular biology, Vol. 26, Issue 11, pp. 4149-60, 2006 (PubMed).

Alternatives for antigen "Docking Protein 1, 62kDa (Downstream of tyrosine Kinase 1) (DOK1)", type "Antibodies"
Hosts (177), (2)
Reactivities (177), (117), (116), (41), (41), (41)
Applications (127), (46), (44), (44), (40), (15), (14), (13), (5), (2), (1), (1)
Conjugates (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (1), (1), (1), (1), (1)
Epitopes (39), (32), (13), (13), (8), (4), (3), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1)
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